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EBV has been proposed to impact immune pathways through molecular mimicry, diverting antibody reactivity towards host tissues. This review explores the literature on EBV\u2010specific similarities with human peptides and cytokines that might contribute to the onset of RA, SLE and MS. In conclusion, it is vital to conduct experimental computational analyses focusing on the homology between EBV and human proteins to unravel the complexities of autoimmune diseases and advance therapeutic approaches. These insights highlight the significance of collaborative efforts and diverse clinical studies for validation, linking the gap between research and practical applications in the complex field of autoimmunity.<\/jats:p>","DOI":"10.1111\/sji.70016","type":"journal-article","created":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T00:18:18Z","timestamp":1743380298000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["The Role of Epstein\u2013Barr Virus Molecular Mimicry in Various Autoimmune Diseases"],"prefix":"10.1111","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6788-7361","authenticated-orcid":false,"given":"Ayesha","family":"Munir","sequence":"first","affiliation":[{"name":"Institute of Zoological Sciences University of Peshawar  Peshawar 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