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The few trials conducted on cognitive behavior therapy (CBT) for anxiety and asthma have mainly targeted panic disorder, and with mixed results. Experimental laboratory research indicates that increased anxiety may lead to hypervigilance toward asthma. Hence, fear and avoidance associated with increased anxiety due to asthma may be an important treatment target. A treatment that learn participants to differentiate between anxiety and asthma through gradual exposure to situations that risk triggering anxiety for asthma may be a possible avenue. As a first step to investigate this issue further, we developed a 10\u2010week exposure\u2010based CBT protocol for anxiety related to asthma and tested it in six participants using multivariate baseline design with repeated assessments throughout treatment. All participants reported satisfaction with treatment, as well as subjective overall improvement after treatment. Visual analysis, using graphs over each individual's trajectory, as well as potential efficacy on group level analyzing standardized mean change, indicated improvements in important outcomes. We conclude that exposure\u2010based CBT is feasible and may improve anxiety related to asthma. Further investigation under randomized controlled trial conditions is warranted.<\/jats:p>","DOI":"10.1111\/sjop.12674","type":"journal-article","created":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T11:27:44Z","timestamp":1595590064000},"page":"827-834","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Exposure\u2010based cognitive behavior therapy for anxiety related to asthma: A feasibility study with multivariate baseline design"],"prefix":"10.1111","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0140-773X","authenticated-orcid":false,"given":"Marianne","family":"Bonnert","sequence":"first","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden"},{"name":"Department of Clinical Neuroscience Centre for Psychiatry Research Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0088-8719","authenticated-orcid":false,"given":"Erik","family":"Andersson","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience Division of Psychology Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7115-6422","authenticated-orcid":false,"given":"Eva","family":"Serlachius","sequence":"additional","affiliation":[{"name":"Department of Clinical Neuroscience Centre for Psychiatry Research Karolinska Institutet Stockholm Sweden"},{"name":"Stockholm Health Care Services Stockholm County Council Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4865-5324","authenticated-orcid":false,"given":"Ida\u2010Kaisa","family":"Manninen","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2483-3296","authenticated-orcid":false,"given":"Sten\u2010Erik","family":"Bergstr\u00f6m","sequence":"additional","affiliation":[{"name":"Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital Karolinska University Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1045-1898","authenticated-orcid":false,"given":"Catarina","family":"Almqvist","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden"},{"name":"Pediatric Allergy and Pulmonology Unit at Astrid Lindgren Children's Hospital Karolinska University Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10608-006-9058-1"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0149-7189(82)90074-X"},{"key":"e_1_2_7_4_1","volume-title":"DUDIT: The drug use disorders identification test manual","author":"Berman A. 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