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However, the neural mechanisms underlying this relationship remain unclear. Using an individual differences approach, the present study examined whether the affective valence of mind wandering is associated with resting\u2010state functional connectivity among brain regions commonly implicated in mind wandering, and whether it mediates the relationship between such connectivity and mood. Resting\u2010state functional magnetic resonance imaging (rs\u2010fMRI) data were acquired from 92 participants, who subsequently completed an experience\u2010sampling film\u2010viewing task to assess mind wandering, its affective valence, and mood. Behavioral results showed that more positively valenced mind wandering was strongly associated with more positive mood. Neuroimaging analyses revealed that the affective valence of mind wandering was positively associated with functional connectivity between the right rostromedial prefrontal cortex (rmPFC) and the left inferior parietal lobule (IPL). Mediation analyses demonstrated that the affective valence of mind wandering mediated the association between this functional connectivity and mood. These findings may support the content regulation hypothesis and the dynamic framework of spontaneous thought.<\/jats:p>","DOI":"10.1111\/sjop.70100","type":"journal-article","created":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T03:18:49Z","timestamp":1776482329000},"page":"1209-1216","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Relationship Between Affective Valence of Mind Wandering and Mood: The Role of Resting\u2010State Functional Connectivity"],"prefix":"10.1111","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0754-8557","authenticated-orcid":false,"given":"Hong","family":"He","sequence":"first","affiliation":[{"name":"Institute of Brain and Psychological Sciences Sichuan Normal University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinghong","family":"Shi","sequence":"additional","affiliation":[{"name":"Institute of Brain and Psychological Sciences Sichuan Normal University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Brain and Psychological Sciences Sichuan Normal University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binqian","family":"Leng","sequence":"additional","affiliation":[{"name":"Institute of Brain and Psychological Sciences Sichuan Normal University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5357-6666","authenticated-orcid":false,"given":"Xuemin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Beijing Key Lab of Applied Experimental Psychology, Faculty of Psychology Beijing Normal University  Beijing China"},{"name":"State Key Laboratory of Cognitive Neuroscience and Learning &amp; IDG\/McGovern Institute for Brain Research Beijing Normal University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,17]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.02.005"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2105-10-209"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn.2016.113"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1220826110"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1162\/jocn.2007.19.6.935"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-9004.2010.00327.x"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.04.034"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41235-018-0129-0"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.1037\/xhp0000743"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsm030"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2016.08.020"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.13740"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.02.039"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.02.052"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2013.00583"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2017.07.006"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2016.02.020"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1037\/emo0001434"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.93689"},{"key":"e_1_2_14_21_1","volume-title":"PROCESS: A Versatile Computational Tool for Observed Variable Mediation, Moderation, and Conditional Process Modeling","author":"Hayes A. 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