{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T22:50:32Z","timestamp":1782168632923,"version":"3.54.5"},"reference-count":64,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,4,20]],"date-time":"2016-04-20T00:00:00Z","timestamp":1461110400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000874","name":"Brain and Behavior Research Foundation","doi-asserted-by":"publisher","award":["19058"],"award-info":[{"award-number":["19058"]}],"id":[{"id":"10.13039\/100000874","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Suicide &amp;amp; Life Threat Behav"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:p>Public health concerns for the independent management of obesity and suicidal behavior are rising. Emerging evidence suggests body weight plays an important role in quantifying the risk of suicide. In light of these findings, we aimed to clarify the association between body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>) and suicidal behavior by systematically reviewing and evaluating the literature. Studies were identified by searching <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> EMBASE<\/jats:styled-content>, Psyc<jats:styled-content style=\"fixed-case\">INFO<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">CINAHL<\/jats:styled-content> from inception to January 2015, supplemented by hand and grey literature searches. Study screening, data extraction, and risk of bias assessment were conducted in duplicate. We included 38 observational studies. Meta\u2010analyses supported an inverse association between <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> and completed suicide. Pooled summary estimates demonstrated that underweight was significantly associated with an increased risk of completed suicide (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u00a0=\u00a01.21, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.07 to 1.36, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.002), and obesity (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u00a0=\u00a00.71, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.56 to 0.89, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.003) and overweight (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\u00a0=\u00a00.78, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.75 to 0.82, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.0001) were significantly associated with a decreased risk of completed suicide relative to normal weight. A qualitative summary of the literature demonstrated conflicting evidence regarding the association between <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> and attempted suicide and revealed no association between <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> and suicidal ideation. <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> may be used to aid the assessment of suicide risk, especially that of completed suicide. However, unmeasured confounders and systematic biases of individual studies limit the quality of evidence.<\/jats:p>","DOI":"10.1111\/sltb.12244","type":"journal-article","created":{"date-parts":[[2016,4,20]],"date-time":"2016-04-20T12:02:52Z","timestamp":1461153772000},"page":"697-736","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":75,"title":["Body Mass Index Is an Important Predictor for Suicide: Results from a Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"46","author":[{"given":"Stefan","family":"Perera","sequence":"first","affiliation":[{"name":"Department of Clinical Epidemiology and Biostatistics McMaster University Hamilton ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca B.","family":"Eisen","sequence":"additional","affiliation":[{"name":"MiNDS Neuroscience Graduate Program McMaster University Hamilton ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittany B.","family":"Dennis","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Biostatistics McMaster University Hamilton ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Bawor","sequence":"additional","affiliation":[{"name":"MiNDS Neuroscience Graduate Program McMaster University Hamilton ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meha","family":"Bhatt","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Biostatistics McMaster University Hamilton ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neera","family":"Bhatnagar","sequence":"additional","affiliation":[{"name":"Health Sciences Library McMaster University Hamilton ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lehana","family":"Thabane","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Biostatistics McMaster University Hamilton ON Canada"},{"name":"Biostatistics Unit Centre for Evaluation of Medicine Hamilton ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell","family":"de Souza","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Biostatistics McMaster University Hamilton ON Canada"},{"name":"Population Genomics Program Chanchlani Research Centre McMaster University Hamilton ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zainab","family":"Samaan","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Biostatistics McMaster University Hamilton ON Canada"},{"name":"Population Genomics Program Chanchlani Research Centre McMaster University Hamilton ON Canada"},{"name":"Department of Psychiatry and Behavioural Neurosciences McMaster University Hamilton ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,4,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAF.0000000000000094"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq274"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwm280"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/rnj.150"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/13811110500318083"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.90.2.251"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291702006943"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwr386"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1027\/0227-5910\/a000115"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2009.07.008"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0803119"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2012.224"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2008.12.002"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00414-012-0776-5"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.17.2028"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/oby.20143"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2009.03.022"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2011.00932.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5215.2010.00452.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/NMD.0000000000000135"},{"key":"e_1_2_7_22_1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/9780470712184.ch7","volume-title":"Cochrane handbook for systematic reviews of interventions","author":"Higgins J. 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