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According to the Interpersonal Theory of Suicide, suicidal behavior becomes likely with the simultaneous presence of perceived burdensomeness (PB), lack of (or thwarted) belongingness (TB), and acquired fearlessness about death (FAD). Here, we examined personality and other variables, including depression, self\u2010esteem, childhood abuse, and substance use, as predictors of these risk factors in cocaine\u2010dependent individuals (CDs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seventy CDs and 70 healthy controls (HCs) participated. We examined group differences in a group\u2010by\u2010sex analysis of variance and identified predictors of PB, TB, and FAD in stepwise regressions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>CDs exhibited elevated PB and TB but not FAD, compared to HCs. CDs also exhibited elevated harm avoidance, novelty seeking, depression, and lower self\u2010esteem and reward dependence. Females reported elevated sexual abuse, harm avoidance, reward dependence, depression, but lower FAD, relative to males, among CDs and HCs. Among CDs, PB was predicted by lower self\u2010esteem and greater emotional abuse; TB was predicted by lower self\u2010esteem and reward dependence, as well as greater emotional and sexual abuse; and FAD was predicted by lower harm avoidance and greater physical abuse.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Interventions targeting suicidality in cocaine dependence should take into consideration self\u2010esteem, personality traits, and childhood abuse.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sltb.12621","type":"journal-article","created":{"date-parts":[[2020,2,7]],"date-time":"2020-02-07T06:23:08Z","timestamp":1581056588000},"page":"867-883","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Interpersonal Risk Factors for Suicide in Cocaine Dependence: Association with Self\u2010Esteem, Personality Traits, and Childhood Abuse"],"prefix":"10.1111","volume":"50","author":[{"given":"Simon","family":"Zhornitsky","sequence":"first","affiliation":[{"name":"Department of Psychiatry Yale University School of Medicine New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thang M.","family":"Le","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Yale University School of Medicine New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isha","family":"Dhingra","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Yale University School of Medicine New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan D.","family":"Adkinson","sequence":"additional","affiliation":[{"name":"Interdepartmental Neuroscience Program Yale University School of Medicine New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Potvin","sequence":"additional","affiliation":[{"name":"Centre de recherche de l'Institut Universitaire en Sant\u00e9 Mentale de Montr\u00e9al Montreal QC Canada"},{"name":"Department of Psychiatry Faculty of Medicine Universit\u00e9 de Montr\u00e9al Montr\u00e9al QC Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiang\u2010shan R.","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Yale University School of Medicine New Haven Connecticut"},{"name":"Interdepartmental Neuroscience Program Yale University School of Medicine New Haven Connecticut"},{"name":"Department of Neuroscience Yale University School of Medicine New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,6]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1590\/1516-4446-2018-0054"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1081\/ADA-120023465"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2014.05.004"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2011.06.044"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph15040636"},{"key":"e_1_2_5_7_1","volume-title":"Manual for the beck depression inventory-II","author":"Beck A. 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