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This cross\u2010sectional study examined the moderating effects of decentering\u2014a cognitive\u2013affective regulation strategy\u2014in the relation between non\u2010suicidal self\u2010injury (NSSI) and suicide ideation via cognitive\u2013affective factors that increase risk for both NSSI and suicide ideation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>College students (<jats:italic>N<\/jats:italic>\u00a0=\u00a0125, 79% women), ages 18\u201327, pre\u2010screened for moderate levels of depression and anxiety, completed self\u2010report measures of NSSI, decentering, rumination, hopelessness, depressive symptoms, and suicide ideation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Young adults with past\u2010year non\u2010suicidal self\u2010injury scored lower on decentering than their peers without NSSI. Decentering was associated with lower levels of all cognitive\u2013affective risk factors and moderated the relation between NSSI and rumination, but not the relation between NSSI and hopelessness and depressive symptoms. Decentering moderated the indirect effect of past\u2010year non\u2010suicidal self\u2010injury on past\u2010week suicide ideation via rumination, but not via hopelessness or depressive symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Decentering is a potential cognitive\u2013affective regulation strategy for targeting factors that increase risk of self\u2010injurious thoughts and behaviors. Future studies should examine decentering as a buffer against risk using designs that allow for conclusions about temporal order of effects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sltb.12747","type":"journal-article","created":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T13:49:10Z","timestamp":1615902550000},"page":"741-754","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Examining decentering as a moderator in the relation between non\u2010suicidal self\u2010injury and suicide ideation via cognitive\u2013affective factors"],"prefix":"10.1111","volume":"51","author":[{"given":"Beverlin","family":"Rosario\u2010Williams","sequence":"first","affiliation":[{"name":"Hunter College and The Graduate Center City University of New York New York City NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simran","family":"Kaur","sequence":"additional","affiliation":[{"name":"Hunter College City University of New York New York City NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7282-9545","authenticated-orcid":false,"given":"Regina","family":"Miranda","sequence":"additional","affiliation":[{"name":"Hunter College and The Graduate Center City University of New York New York City NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,3,16]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Manual for the Beck scale for suicide ideation","author":"Beck A. 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