{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T13:08:57Z","timestamp":1791637737434,"version":"4.3.4"},"reference-count":79,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,1,27]],"date-time":"2024-01-27T00:00:00Z","timestamp":1706313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002428","name":"Austrian Science Fund","doi-asserted-by":"publisher","award":["KLI963\u2010B"],"award-info":[{"award-number":["KLI963\u2010B"]}],"id":[{"id":"10.13039\/501100002428","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005788","name":"Medizinische Universit\u00e4t Wien","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005788","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Suicide &amp;amp; Life Threat Behav"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Mentalization\u2010based therapy (MBT) and its adapted version for adolescents (MBT\u2010A) are repeatedly highlighted as promising treatments for reducing self\u2010harm, particularly in borderline personality disorder (BPD). Despite the availability of publications providing evidence of their efficacy in reducing self\u2010harm, recent meta\u2010analyses have yielded mixed results. To inform best\u2010practice clinical decision\u2010making, we conducted a systematic review and meta\u2010analysis. We aimed to disentangle findings for both adolescents and adults on the efficacy of MBT(\u2010A) in reducing self\u2010harm (primary outcome) and symptoms of BPD and depression (secondary outcomes).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Web of Science, Scopus, Embase, PubMed\/Medline, and Cochrane Review Database were searched for eligible studies published until September 2022. In total, 14 studies were identified, comprising 612 participants from nine MBT studies (six pre\u2013post, three RCTs) and five MBT\u2010A studies (two pre\u2013post, three RCTs). Aggregated effect sizes were estimated using random\u2010effects models. Meta\u2010regressions were conducted to assess the effect of moderator variables (treatment duration, drop\u2010out rates, and age) on effect sizes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, both MBT and MBT\u2010A demonstrated promising effects in reducing self\u2010harm (\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u2009\u22120.82, 95% CI \u22121.15 to \u22120.50), borderline personality disorder (\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u2009\u22121.08, 95% CI \u22121.38 to \u22120.77), and depression (\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u2009\u22121.1, 95% CI \u22121.52 to \u22120.68) symptoms. However, when compared to control interventions (TAU, SCM), MBT(\u2010A) did not prove to be more efficacious, with the exception of MBT showing superior effects on BPD symptoms in adults (\n                      <jats:italic>g<\/jats:italic>\n                      \u2009=\u2009\u22120.56, 95% CI \u22120.88 to \u22120.24).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although the pre\u2013post evaluations seem promising, this analysis, including RCTs, showed no superiority of MBT(\u2010A) to control conditions, so that prioritizing the application of MBT (\u2010A) for the treatment of self\u2010harm is not supported. Possible explanations and further implications are discussed.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/sltb.13044","type":"journal-article","created":{"date-parts":[[2024,1,27]],"date-time":"2024-01-27T03:38:49Z","timestamp":1706326729000},"page":"317-337","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Efficacy of mentalization\u2010based therapy in treating self\u2010harm: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5734-1293","authenticated-orcid":false,"given":"Carola","family":"Hajek\u00a0Gross","sequence":"first","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Medical University Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0633-5827","authenticated-orcid":false,"given":"Sofia\u2010Marie","family":"Oehlke","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Medical University Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9835-1850","authenticated-orcid":false,"given":"Karin","family":"Prillinger","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Medical University Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8994-964X","authenticated-orcid":false,"given":"Andreas","family":"Goreis","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Medical University Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4333-1494","authenticated-orcid":false,"given":"Paul L.","family":"Plener","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Medical University Vienna  Vienna Austria"},{"name":"Department of Child and Adolescent Psychiatry and Psychotherapy University of Ulm  Ulm Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3243-0238","authenticated-orcid":false,"given":"Oswald D.","family":"Kothgassner","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Medical University Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1521\/pedi.2012.26.4.568"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291718002878"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbtep.2016.04.006"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.156.10.1563"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/med\/9780198570905.001.0001"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2009.09040539"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpp.13152"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2353"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsm009"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1037\/per0000210"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.copsyc.2020.06.008"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jclp.22150"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1162\/jocn.2009.21121"},{"key":"e_1_2_9_15_1","volume-title":"Applied meta\u2010analysis for social science research","author":"Card N. 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