{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T13:37:23Z","timestamp":1790775443944,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,4,6]],"date-time":"2017-04-06T00:00:00Z","timestamp":1491436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012631","name":"TOBE MAKI Scholarship Foundation","doi-asserted-by":"crossref","award":["16-JC-005"],"award-info":[{"award-number":["16-JC-005"]}],"id":[{"id":"10.13039\/501100012631","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scandinavian Med Sci Sports"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:p>This study examined localization of muscle damage within the quadriceps femoris induced by different types of eccentric exercises by using transverse relaxation time (<jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub>)\u2010weighted magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>). Thirty\u2010three young males performed either of the following three exercises: single\u2010joint eccentric contraction of the knee extensors (<jats:styled-content style=\"fixed-case\">KE<\/jats:styled-content>), eccentric squat (S), or downhill walking (<jats:styled-content style=\"fixed-case\">DW<\/jats:styled-content>) (n=11\/exercise). <jats:styled-content style=\"fixed-case\">KE<\/jats:styled-content> and S consisted of 5\u2010set\u00d710\u2010lowering of 90% one\u2010repetition maximum load. <jats:styled-content style=\"fixed-case\">DW<\/jats:styled-content> was performed for 60\u00a0minutes with \u221210% slope, 6\u00a0km\/h velocity, and 20% body mass load carried. At pre\u2010 and 24\u2010, 48\u2010, and 72\u2010hours post\u2010exercise, <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub>\u2010<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> was scanned and <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> values for the rectus femoris (<jats:styled-content style=\"fixed-case\">RF<\/jats:styled-content>), vastus intermedius (<jats:styled-content style=\"fixed-case\">VI<\/jats:styled-content>), vastus lateralis (<jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content>), and vastus medialis (<jats:styled-content style=\"fixed-case\">VM<\/jats:styled-content>) at proximal, middle, and distal sites were calculated. Additionally, soreness felt when static pressure was applied to these sites and maximal isometric knee extension torque were measured. Maximal torque significantly (<jats:italic>P<\/jats:italic>&lt;.05) decreased (7%\u201015%) at 24\u201048\u00a0hours after all exercises. <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> significantly increased (3%\u20109%) at 24\u201072\u00a0hours after all exercises, with heterogeneities within the muscles found in each exercise. Effect size and peak change of <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub>, as well as soreness, overall indicated that the proximal <jats:styled-content style=\"fixed-case\">RF<\/jats:styled-content> after <jats:styled-content style=\"fixed-case\">KE<\/jats:styled-content> and middle <jats:styled-content style=\"fixed-case\">VM<\/jats:styled-content> after S and <jats:styled-content style=\"fixed-case\">DW<\/jats:styled-content> were most affected by these exercises. The <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content> did not show any significant <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> increase after all exercises. These results suggest that muscle damage specifically localizes at the proximal <jats:styled-content style=\"fixed-case\">RF<\/jats:styled-content> by <jats:styled-content style=\"fixed-case\">KE<\/jats:styled-content> and at the middle <jats:styled-content style=\"fixed-case\">VM<\/jats:styled-content> by S and <jats:styled-content style=\"fixed-case\">DW<\/jats:styled-content>, while the <jats:styled-content style=\"fixed-case\">VL<\/jats:styled-content> is least damaged regardless of the exercises.<\/jats:p>","DOI":"10.1111\/sms.12880","type":"journal-article","created":{"date-parts":[[2017,3,17]],"date-time":"2017-03-17T20:46:38Z","timestamp":1489783598000},"page":"95-106","source":"Crossref","is-referenced-by-count":50,"title":["Localization of muscle damage within the quadriceps femoris induced by different types of eccentric 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