{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:37:25Z","timestamp":1791679045564,"version":"4.3.4"},"reference-count":53,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,7,26]],"date-time":"2018-07-26T00:00:00Z","timestamp":1532563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006808","name":"University of North Carolina","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006808","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scandinavian Med Sci Sports"],"published-print":{"date-parts":[[2018,11]]},"abstract":"Neuromuscular function in young overweight\/obese (OF<\/jats:styled-content>) children is not well described.<\/jats:p><\/jats:sec>Aim<\/jats:title>This study examined isometric and isokinetic leg extensor strength, muscle size (mCSA<\/jats:styled-content>) and tissue composition as measured via echo intensity (mEI<\/jats:styled-content>), and motor unit (MU<\/jats:styled-content>) firing rates in normal weight (NW<\/jats:styled-content>) and OF<\/jats:styled-content> children aged 7\u201010\u00a0years.<\/jats:p><\/jats:sec>Methods<\/jats:title>Fourteen NW<\/jats:styled-content> (eight girls and six boys, BMI<\/jats:styled-content>: 15.8\u00a0\u00b1\u00a01.4\u00a0kg\/m2<\/jats:sup>) and 15 OF<\/jats:styled-content> (10 girls and five boys, BMI<\/jats:styled-content>: 20.8\u00a0\u00b1\u00a02.3\u00a0kg\/m2<\/jats:sup>) children volunteered to perform this study. Percentage body fat (%BF<\/jats:styled-content>) was measured, and mCSA<\/jats:styled-content>, mEI<\/jats:styled-content>, and subcutaneous fat (sFAT<\/jats:styled-content>) of the vastus lateralis (VL<\/jats:styled-content>) was assessed. MU<\/jats:styled-content> mean firing rates (MFR<\/jats:styled-content>s) in relation to recruitment threshold (RT<\/jats:styled-content>) of the VL<\/jats:styled-content> were assessed during submaximal isometric contractions. Maximal isokinetic contractions were performed at 1.05 and 4.20\u00a0rad\/s. The 95% confidence intervals (CI<\/jats:styled-content>) from the statistical tests are presented.<\/jats:p><\/jats:sec>Results<\/jats:title>The OF<\/jats:styled-content> children had greater %BF<\/jats:styled-content> (95% CI<\/jats:styled-content>\u00a0=\u00a0\u221215.1 to \u22127.2), mCSA<\/jats:styled-content> (95% CI<\/jats:styled-content>\u00a0=\u00a0\u22124.1 to \u22121.2), mEI<\/jats:styled-content> (95% CI<\/jats:styled-content>\u00a0=\u00a0\u221222.3 to \u22125.9), and sFAT<\/jats:styled-content> (95% CI<\/jats:styled-content>\u00a0=\u00a0\u22120.5 to \u22120.1), greater rate of strength loss with increasing isokinetic velocities (95% CI<\/jats:styled-content>\u00a0=\u00a00.4 to 5.4), and a smaller range of MFR<\/jats:styled-content>s (95% CI<\/jats:styled-content>\u00a0=\u00a00.007 to 7.136) at the steady torque than the NW<\/jats:styled-content> children.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>The OF<\/jats:styled-content> children had poorer muscle tissue composition, greater velocity\u2010related impairments in muscle strength, and a smaller range of MFR<\/jats:styled-content>s at the targeted torque that may suggest altered MU<\/jats:styled-content> recruitment strategies. Interventions in OF<\/jats:styled-content> children should include exercises and recruit higher\u2010threshold MU<\/jats:styled-content>s, such as high\u2010intensity resistance exercises.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sms.13256","type":"journal-article","created":{"date-parts":[[2018,6,30]],"date-time":"2018-06-30T13:44:28Z","timestamp":1530366268000},"page":"2310-2321","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Examination of muscle morphology and neuromuscular function in normal weight and overfat children aged 7\u201010 years"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5555-5156","authenticated-orcid":false,"given":"Trent J.","family":"Herda","sequence":"first","affiliation":[{"name":"Neuromechanics Laboratory University of Kansas Lawrence Kansas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric 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