{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T09:50:43Z","timestamp":1787737843838,"version":"build-2784847793"},"reference-count":23,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T00:00:00Z","timestamp":1594944000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["536001001"],"award-info":[{"award-number":["536001001"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scandinavian Med Sci Sports"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Achilles tendinopathy (AT) occurs in half of the elite runners. AT is a difficult\u2010to\u2010treat tendon disease, which may progress from new onset to a chronic state. It is unknown how many runners with new\u2010onset AT develop persisting symptoms and which prognostic factors are associated with this course.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe how many runners develop persisting symptoms 1\u00a0year after onset of reactive AT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Runners registering for a Dutch running event (5\u201042.2\u00a0km) were eligible for inclusion. Runners reporting new\u2010onset AT between registration for the running event and 1\u00a0month after received a 1\u2010year follow\u2010up questionnaire. The 1\u2010year follow\u2010up questionnaire inquired about persisting symptoms (yes\/no), running activity, and metabolic disorders. We calculated the percentage of runners with persisting symptoms and performed a multivariable logistic regression analysis to study the association between potential prognostic factors and persisting symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 1929 participants, 100 runners (5%) reported new\u2010onset AT. A total of 62 runners (62%) filled in the 1\u2010year follow\u2010up questionnaire. Persisting symptoms were reported by 20 runners (32%). A higher running distance per week before new\u2010onset AT was associated with a lower risk of developing persisting symptoms (odds ratio (OR): 0.9, 95% confidence interval (CI): [0.9;1.0]). There was a positive trend toward an association between metabolic disorders and persisting symptoms (OR: 5.7, 95% CI: [0.9;36.2]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>One third of runners develop persisting symptoms 1\u00a0year after new\u2010onset AT. Interestingly, a higher running distance per week before new\u2010onset AT potentially lowers the risk of developing persisting symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sms.13760","type":"journal-article","created":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T21:03:45Z","timestamp":1593723825000},"page":"1939-1948","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["How many runners with new\u2010onset Achilles tendinopathy develop persisting symptoms? A large prospective cohort study"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4550-8284","authenticated-orcid":false,"given":"Iris F.","family":"Lagas","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine Erasmus MC University Medical Center Rotterdam Zuid\u2010Holland The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3767-2770","authenticated-orcid":false,"given":"Tryntsje","family":"Fokkema","sequence":"additional","affiliation":[{"name":"Department of General Practice Erasmus MC University Medical Center Rotterdam Zuid\u2010Holland The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sita M. A.","family":"Bierma\u2010Zeinstra","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine Erasmus MC University Medical Center Rotterdam Zuid\u2010Holland The Netherlands"},{"name":"Department of General Practice Erasmus MC University Medical Center Rotterdam Zuid\u2010Holland The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan A. 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