{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T02:26:35Z","timestamp":1785551195789,"version":"3.56.0"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T00:00:00Z","timestamp":1639008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011890","name":"Wesley Medical Research","doi-asserted-by":"publisher","award":["#2015\u201017"],"award-info":[{"award-number":["#2015\u201017"]}],"id":[{"id":"10.13039\/100011890","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scandinavian Med Sci Sports"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the short\u2010 and long\u2010term effects of high\u2010intensity interval training (HIIT) with usual care moderate intensity continuous training (MICT) on systemic vascular function and stiffness in patients with coronary artery disease undergoing a cardiac rehabilitation program.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Randomized controlled trial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010four patients (age\u00a0=\u00a063\u00a0\u00b1\u00a08\u00a0years, 93% male) were randomized to complete 3\u00a0sessions\/week (2\u00a0supervised, 1\u00a0home\u2010based) of either (1) 4\u00a0\u00d7\u00a04\u2010min HIIT or (2) 40\u2010min MICT, for 4\u00a0weeks. Patients then continued 3 unsupervised home\u2010based sessions\/week of their allocated training for 11\u00a0months. Brachial artery flow\u2010mediated dilation, pulse wave velocity, and blood pressure were measured at baseline, 4\u00a0weeks, 3\u00a0months, 6\u00a0months, and 12\u00a0months. Data were analyzed using linear mixed modeling and are presented as mean change from baseline (95% CI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>HIIT showed a greater improvement in flow\u2010mediated dilation compared to MICT after 4\u00a0weeks [1.5% (0.9, 2.1) vs 0.1% (\u22120.5, 0.8); <jats:italic>p\u00a0<\/jats:italic>=\u00a00.004) but not 12\u00a0months [1.2% (\u22120.2, 2.5) vs 0.4% (\u22120.8, 1.7); <jats:italic>p\u00a0<\/jats:italic>=\u00a00.153). There were no short\u2010 or long\u2010term group differences for changes in pulse wave velocity, peripheral or central blood pressure between HIIT and MICT after 4\u00a0weeks, or over 12\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A 4\u2010week HIIT program was superior to MICT for improving vascular function, but not arterial stiffness or blood pressure. Over 12\u00a0months, changes in vascular function, blood pressure, and arterial stiffness were similar for HIIT and MICT.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sms.14106","type":"journal-article","created":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T12:08:52Z","timestamp":1637928532000},"page":"512-520","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Comparison of high intensity interval training with standard cardiac rehabilitation on vascular function"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0073-2714","authenticated-orcid":false,"given":"Jenna L.","family":"Taylor","sequence":"first","affiliation":[{"name":"Centre for Research on Exercise, Physical Activity, and Health (CREXPAH) School of Human Movement and Nutrition Sciences University of Queensland  Brisbane Australia"},{"name":"Physiology and Ultrasound Laboratory in Science and Exercise (PULSE) School 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