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Mean differences were calculated using random\u2010effects model. The certainty of the evidence was assessed with GRADE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010seven RCTs (18 HIIT and 9 RTS) were analyzed, with median duration of 12\u2009weeks. Participants' (<jats:italic>n<\/jats:italic>\u00a0=\u00a0946) median age was 46\u2009years. Overall, IHIE decreased SBP (\u22123.29\u2009mmHg; 95% CI: \u22125.19, \u22121.39) and DBP (\u22122.62\u2009mmHg; 95% CI: \u22123.79, \u22121.44) compared to the control group. IHIE elicited higher decreases in office SBP and DBP of hypertensive subjects (SBP: \u22127.13\u2009mmHg, [95% CI: \u221210.12, \u22124.15]; DBP: \u22125.81\u2009mmHg, [95% CI: \u22127.94, \u22123.69]) than pre\u2010hypertensive (SBP: \u22122.14\u2009mmHg, [95% CI: \u22124.36, \u22120.08]; DBP: \u22121.83\u2009mmHg, [95% CI: \u22122.99, \u22120.67]). No significant differences were found between HIIT (SBP: \u22122.12\u2009mmHg, [95% CI: \u22124.78, \u22120.54]; DBP: \u22121.89\u2009mmHg, [95% CI: \u22123.32, \u22120.48]) and RTS (SBP: \u22124.18\u2009mmHg, [95% CI: \u22127.19, \u22122.43]; DBP: \u22124.04\u2009mmHg, [95% CI: \u22126.00, \u22122.09]). These findings present low\/very low certainty of evidence. No adverse cardiovascular events were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>IHIE appears to be safe and to promote substantial decreases in BP, particularly in patients with hypertension. However, the certainty of evidence was low\/very low.<\/jats:p><\/jats:sec><jats:sec><jats:title>Protocol<\/jats:title><jats:p>CRD42020163575.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sms.14299","type":"journal-article","created":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T11:39:47Z","timestamp":1672313987000},"page":"364-381","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Intermittent high\u2010intensity exercise for pre\u2010 to established hypertension: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2726-3332","authenticated-orcid":false,"given":"Jorge M. M.","family":"Teixeira","sequence":"first","affiliation":[{"name":"Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD) University of Maia  Maia Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3265-7838","authenticated-orcid":false,"given":"Daisy","family":"Motta\u2010Santos","sequence":"additional","affiliation":[{"name":"Sports Department, School of Physical Education, Physiotherapy and Occupational Therapy Federal University of Minas Gerais  Belo Horizonte Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3224-0506","authenticated-orcid":false,"given":"Zoran","family":"Milanovic","sequence":"additional","affiliation":[{"name":"Faculty of Sport and Physical Education University of Ni\u0161  Ni\u0161 Serbia"},{"name":"Science and Research Centre Koper Institute for Kinesiology Research  Koper Slovenia"},{"name":"Faculty of Sports Studies, 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