{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T02:20:26Z","timestamp":1784600426262,"version":"3.55.0"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,2,3]],"date-time":"2023-02-03T00:00:00Z","timestamp":1675382400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scandinavian Med Sci Sports"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>Recent evidence indicates that low\u2010load blood flow restriction (LL\u2010BFR) training elicits an anabolic response in tendinous tissue. The purpose of the present study was to investigate the hypertrophic pattern induced in the Achilles tendon by LL\u2010BFR, in comparison with the regional hypertrophy typically observed with conventional high\u2010load (HL) resistance training.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:italic>N<\/jats:italic>\u00a0=\u00a040 male participants were randomly and concealed allocated to one of two groups: LL\u2010BFR training (20\u201335% one\u2010repetition maximum\/1RM) or HL training (70\u201385% 1RM). The training was completed three times per week for a total of 14\u2009weeks. Before and after the training period, Achilles tendon morphology was assessed using magnetic resonance imaging along the entire tendon length. Additionally, dynamic strength measures of the plantar flexors were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In line with previous findings, dynamic plantar flexion strength was improved to a comparable extent in both groups (LL\u2010BFR: 43.6%; HL: 43.5%). The results also confirmed significant increases in Achilles tendon cross\u2010sectional area with LL\u2010BFR (+5.2%). Moreover, they revealed that the hypertrophic pattern obtained with LL\u2010BFR was similar to regional changes seen with conventional HL training.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present findings point towards the notion that despite the low loads being applied, LL\u2010BFR training induces Achilles tendon hypertrophy by potentiating anabolic responses in the same regions as with conventional high\u2010load training. Future studies are needed to (i) focus on the potential mechanisms underlying these tendon morphology changes and (ii) apply and evaluate LL\u2010BFR training in clinical populations to validate these results in rehabilitative settings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/sms.14321","type":"journal-article","created":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T04:53:45Z","timestamp":1674795225000},"page":"848-856","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Similar patterns of tendon regional hypertrophy after low\u2010load blood flow restriction and high\u2010load resistance training"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6839-4438","authenticated-orcid":false,"given":"Christoph","family":"Centner","sequence":"first","affiliation":[{"name":"Department of Sport and Sport Science University of Freiburg  Freiburg Germany"},{"name":"Praxisklinik Rennbahn  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