{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T03:09:07Z","timestamp":1792120147387,"version":"4.4.0"},"reference-count":41,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T00:00:00Z","timestamp":1719705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006196","name":"Oulun Yliopisto","doi-asserted-by":"publisher","award":["24000692"],"award-info":[{"award-number":["24000692"]}],"id":[{"id":"10.13039\/501100006196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006393","name":"Universidad de Granada","doi-asserted-by":"publisher","award":["SOMM17\/6107\/UGR"],"award-info":[{"award-number":["SOMM17\/6107\/UGR"]}],"id":[{"id":"10.13039\/501100006393","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scandinavian Med Sci Sports"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The beneficial effects of physical activity (PA) on gut microbiome have been reported, nevertheless the findings are inconsistent, with the main limitation of subjective methods for assessing PA. It is well accepted that using an objective assessment of PA reduces the measurement error and also allows objective assessment of sedentary behavior (SB). We aimed to study the associations between accelerometer\u2010assessed behaviors (i.e., SB, light\u2010intensity physical activity [LPA] and moderate\u2010to\u2010vigorous physical activity [MVPA]) with the gut microbiome using compositional data analysis, a novel approach that enables to study these behaviors accounting for their inter\u2010dependency. This cross\u2010sectional study included 289 women from the Northern Finland Birth Cohort 1966. Physical activity was measured during 14\u2009days by wrist\u2010worn accelerometers. Analyses based on the combined effect of MVPA and SB, and compositional data analyses in association with the gut microbiome data were performed. The microbial alpha\u2010 and beta\u2010diversity were not significantly different between the MVPA\u2010SB groups, and no differentially abundant microorganisms were detected. Compositional data analysis did not show any significant associations between any movement behavior (relative to the others) on microbial alpha\u2010diversity. Butyrate\u2010producing bacteria such as\n                    <jats:italic>Agathobacter<\/jats:italic>\n                    and\n                    <jats:italic>Lachnospiraceae<\/jats:italic>\n                    CAG56 were significantly more abundant when reallocating time from LPA or SB to MVPA (\n                    <jats:italic>\u03b3<\/jats:italic>\n                    \u2009=\u20090.609 and 0.113, both\n                    <jats:italic>p<\/jats:italic>\n                    \u2010values\u2009=\u20090.007). While PA and SB were not associated with microbial diversity, we found associations of these behaviors with specific gut bacteria, suggesting that PA of at least moderate intensity (i.e., MVPA) could increase the abundance of short\u2010chain fatty acid\u2013producing microbes.\n                  <\/jats:p>","DOI":"10.1111\/sms.14689","type":"journal-article","created":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T02:48:28Z","timestamp":1719802108000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Association of Accelerometer\u2010Determined Physical Activity and Sedentary Behavior With the Gut Microbiome in Middle\u2010Aged Women: A Compositional Data Approach"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1141-9187","authenticated-orcid":false,"given":"Inmaculada","family":"P\u00e9rez\u2010Prieto","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Molecular Biology I, Faculty of Sciences University of Granada  Granada Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria ibs.GRANADA  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jairo\u00a0H.","family":"Migueles","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sports, Faculty of Sport Sciences Sport and Health University Research Institute (iMUDS), University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nerea\u00a0M.","family":"Molina","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology I, Faculty of Sciences University of Granada  Granada Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria ibs.GRANADA  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Sola\u2010Leyva","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology Karolinska Institutet  Huddinge Stockholm Sweden"},{"name":"Department of Gynaecology and Reproductive Medicine Karolinska University Hospital  Huddinge Stockholm Sweden"},{"name":"Competence Centre on Health Technologies  Tartu Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Salas\u2010Espejo","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology I, Faculty of Sciences University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riikka\u00a0K.","family":"Arffman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Center Oulu University Hospital, University of Oulu  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjukka","family":"Nurkkala","sequence":"additional","affiliation":[{"name":"Department of Sports and Exercise Medicine Oulu Deaconess Institute Foundation sr  Oulu Finland"},{"name":"Research Unit of Population Health, Faculty of Medicine University of Oulu  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1008-3263","authenticated-orcid":false,"given":"Maisa","family":"Niemel\u00e4","sequence":"additional","affiliation":[{"name":"Research Unit of Health Sciences and Technology, Medical Faculty University of Oulu  Oulu Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kreete","family":"L\u00fcll","sequence":"additional","affiliation":[{"name":"Institute of Genomics, Estonian Genome Centre, University of Tartu  Tartu Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elin","family":"Org","sequence":"additional","affiliation":[{"name":"Institute of Genomics, Estonian Genome Centre, University of Tartu  Tartu Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Franks","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Metabolism, Digestion and Reproduction Imperial College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juha\u00a0S.","family":"Tapanainen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Helsinki and Helsinki University Hospital  Helsinki Finland"},{"name":"Department of Obstetrics and Gynaecology HFR \u2013 Cantonal Hospital of Fribourg and University of Fribourg  Fribourg Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres","family":"Salumets","sequence":"additional","affiliation":[{"name":"Division of Obstetrics and Gynecology, Department of Clinical Science, Intervention and Technology Karolinska Institutet  Huddinge Stockholm Sweden"},{"name":"Department of Gynaecology and Reproductive Medicine Karolinska University Hospital  Huddinge Stockholm Sweden"},{"name":"Competence Centre on Health Technologies  Tartu Estonia"},{"name":"Department of Obstetrics and Gynaecology Institute of Clinical Medicine, University of Tartu  Tartu Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terhi\u00a0T.","family":"Piltonen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Research Unit of Clinical Medicine, Medical Research Center Oulu University Hospital, University of Oulu  Oulu 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