{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T18:06:06Z","timestamp":1781114766258,"version":"3.54.1"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T00:00:00Z","timestamp":1748044800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T00:00:00Z","timestamp":1748044800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scandinavian Med Sci Sports"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The purpose of this study was to explore between\u2010limb differences in gluteal, quadriceps, hamstring, and triceps surae muscle size and activity during a repeated vertical jump\u2010landing task in individuals with a history of unilateral anterior cruciate ligament reconstruction (ACLR). Twelve recreationally active participants with a unilateral history of ACLR involving a semitendinosus autograft (1\u20132.5\u2009years post\u2010surgery) underwent functional magnetic resonance imaging (fMRI) before and immediately after 60 vertical jumps. Exercise\u2010induced increases in transverse (T2) relaxation times and resting muscle volumes were measured in 12 lower limb muscles. Linear mixed models were used to explore differences between the ACLR and uninjured contralateral limb, as well as their relationship with vertical jump performance. Reconstructed limbs displayed smaller muscle volumes in vastus medialis (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.028), rectus femoris (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.019), semitendinosus (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), and gastrocnemius lateral head (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.028) than homonymous muscles in the uninjured contralateral limb. Limbs with a history of ACLR also exhibited smaller percentage changes in T2 relaxation time for semitendinosus (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), semimembranosus (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.002), lateral gastrocnemius (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.014), and soleus (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.008), while the vastus lateralis displayed a greater increase (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.001) than uninjured contralateral limbs. Between\u2010limb asymmetry in quadriceps muscle volume and activity was associated with between\u2010limb asymmetry in vertical jump\u2010landing impulse (r\n                    <jats:sup>2<\/jats:sup>\n                    \u2009=\u20090.30\u20130.34). The findings from this study may help to inform the design of exercise interventions aimed at restoring lower limb function and reducing reinjury risk in individuals with a history of ACLR.\n                  <\/jats:p>","DOI":"10.1111\/sms.70079","type":"journal-article","created":{"date-parts":[[2025,5,24]],"date-time":"2025-05-24T03:04:39Z","timestamp":1748055879000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Altered Metabolic Activity and Morphology of Lower Limb Muscles 1\u20132\u2009Years Following Anterior Cruciate Ligament Reconstruction"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8747-3796","authenticated-orcid":false,"given":"Benjamin","family":"Dutaillis","sequence":"first","affiliation":[{"name":"School of Health Sciences and Social Work Griffith University, Gold Coast Campus  Gold Coast Australia"},{"name":"Australian Centre for Precision Health and Technology (PRECISE) Griffith University, Gold Coast Campus  Gold Coast Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2050-6442","authenticated-orcid":false,"given":"Tyler","family":"Collings","sequence":"additional","affiliation":[{"name":"School of Health Sciences and Social Work Griffith University, Gold Coast Campus  Gold Coast Australia"},{"name":"Australian Centre for Precision Health and Technology (PRECISE) Griffith University, Gold Coast Campus  Gold Coast Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7266-2976","authenticated-orcid":false,"given":"Philip","family":"Bellinger","sequence":"additional","affiliation":[{"name":"School of Health Sciences and Social Work Griffith University, Gold Coast Campus  Gold Coast Australia"},{"name":"Griffith Sport Science Griffith University, Gold Coast Campus  Gold Coast Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4964-1848","authenticated-orcid":false,"given":"Ryan G.","family":"Timmins","sequence":"additional","affiliation":[{"name":"School of Behavioural and Health Sciences Australian Catholic University  Brisbane Australia"},{"name":"The Sports Performance, Recovery, Injury and New Technologies (SPRINT) Research Centre  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1410-9843","authenticated-orcid":false,"given":"Benjamin","family":"Kennedy","sequence":"additional","affiliation":[{"name":"School of Health Sciences and Social Work Griffith University, Gold Coast Campus  Gold Coast Australia"},{"name":"Mermaid Beach Radiology  Gold Coast Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3374-4669","authenticated-orcid":false,"given":"Matthew 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