{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T00:46:49Z","timestamp":1783730809255,"version":"3.55.0"},"reference-count":42,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T00:00:00Z","timestamp":1751932800000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000980","name":"Arthritis Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000980","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scandinavian Med Sci Sports"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Aberrant gait biomechanics following anterior cruciate ligament (ACL) injury and ACL reconstruction (ACLR) are critical factors contributing to the development of knee osteoarthritis (KOA). However, it remains unknown how ACLR impacts lower extremity joint energetics and each joint's contribution to total limb energetics during walking. To compare mechanical energetics at the ankle, knee, and hip joints between ACLR limbs, contralateral, and control limbs during walking. Forty\u2010four participants with primary unilateral ACLR (post\u2010ACLR: 6.0\u2009\u00b1\u20090.2\u2009months) and 44 uninjured controls were studied. Ankle, knee, and hip joint work were calculated as the time integral of the negative (energy dissipation) or positive (energy generation) regions of the respective stance\u2010phase joint power curves. The joint\u2010specific contribution to total limb energy dissipation and generation was calculated. ANCOVA was used to assess differences in energy dissipation and generation at the ankle, knee, and hip between ACLR, contralateral, and matched control limbs, respectively. Compared to contralateral and matched control limbs, ACLR limbs exhibited lesser energy dissipation (ACLR: \u22120.06\u2009\u00b1\u20090.03\u2009J\/kg; vs. contralateral: \u22120.12\u2009\u00b1\u20090.07; vs. control: \u22120.12\u2009\u00b1\u20090.04; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, all) and generation (0.08\u2009\u00b1\u20090.03 vs. 0.11\u2009\u00b1\u20090.06 vs. 0.10\u2009\u00b1\u20090.04; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, all) about the knee joint and lesser contribution from the knee (66.8\u2009\u00b1\u200933.0 vs. 79.8\u2009\u00b1\u200926.7 vs. 79.9\u2009\u00b1\u200923.1; <jats:italic>p<\/jats:italic>\u2009=\u20090.01, all) and greater contribution from the hip (30.5\u2009\u00b1\u200933.1 vs. 14.5\u2009\u00b1\u200923.5 vs. 14.7\u2009\u00b1\u200919.8; <jats:italic>p<\/jats:italic>\u2009=\u20090.004 and <jats:italic>p<\/jats:italic>\u2009=\u20090.003, respectively) to total limb generation during mid\u2010stance. Compared to contralateral limbs and matched controls, individuals at 6\u2009months post ACLR exhibit altered lower extremity mechanical energetics, with decreased knee contributions and a greater hip contribution during walking.<\/jats:p>","DOI":"10.1111\/sms.70105","type":"journal-article","created":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T06:29:02Z","timestamp":1751956142000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Lower Extremity Mechanical Energetics During Walking 6\u2009Months Following Anterior Cruciate Ligament Reconstruction"],"prefix":"10.1111","volume":"35","author":[{"given":"Hyunwook","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Sport, Health, and Rehabilitation Kookmin University  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Lisee","sequence":"additional","affiliation":[{"name":"Department of Kinesiology University of Georgia  Athens Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christin","family":"B\u00fcttner","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sport Science University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Bjornsen","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sport Science University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Favoreto","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sport Science University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Creighton","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, School of Medicine University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganesh M.","family":"Kamath","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, School of Medicine University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey T.","family":"Spang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, School of Medicine University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason R.","family":"Franz","sequence":"additional","affiliation":[{"name":"Joint Department of Biomedical Engineering University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"},{"name":"Joint Department of Biomedical Engineering North Carolina State University  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Troy","family":"Blackburn","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sport Science University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Pietrosimone","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sport Science University of North Carolina at Chapel Hill  Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062\u20106050\u201049.3.35"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062\u20106050\u201049.3.89"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439\u2010014\u20101117\u20102"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.bor.0000240365.16842.4e"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0000000000002208"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2012.02.004"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2010.07.013"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0966\u20106362(02)00068\u20101"},{"issue":"3","key":"e_1_2_9_10_1","first-page":"517","article-title":"Post\u2010Traumatic Osteoarthritis: The Role of Stress Induced Chondrocyte Damage","volume":"43","author":"Martin J. 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