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M\u00f8ller og Hustru Chastine Mc-Kinney M\u00f8llers Fond til almene Formaal","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005747","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007437","name":"TrygFonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007437","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Scandinavian Med Sci Sports"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Children and adolescents with overweight or obesity are less physically active than their lean counterparts. We examined the effects of adding a 3\u2010month high\u2010intensity interval training (HIIT) program to a 12\u2010month lifestyle intervention on physical activity (PA) in children and adolescents with overweight or obesity. Participants were randomized to a 12\u2010month lifestyle intervention (control,\n                    <jats:italic>N<\/jats:italic>\n                    \u2009=\u200983) or a 12\u2010month lifestyle intervention with a 3\u2010month HIIT program (HIIT,\n                    <jats:italic>N<\/jats:italic>\n                    \u2009=\u200990). PA was assessed using accelerometry at baseline, and subsequently at 3 and 12\u2009months. Linear mixed models estimated the mean difference in PA intensity between groups. Associations were explored using Pearson's correlation coefficient. The HIIT group showed a greater increase in moderate\u2010to\u2010vigorous PA (MVPA) after 3\u2009months (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.04), with a mean increase of 8.3\u2009min per day (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.01) compared to 0.9\u2009min per day (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.75) in the control group. At 12\u2009months, there was no difference between the groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.64), and MVPA returned to baseline levels. Across randomization, sedentary time increased by 17.5\u2009min per day (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.02) at 3\u2009months and by 29.9\u2009min per day (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.01) at 12\u2009months. Changes from baseline to 12\u2009months in vigorous activity were inversely correlated with changes in BMI\n                    <jats:italic>z<\/jats:italic>\n                    \u2010score (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u2009\u22120.26,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.02). Adding a 3\u2010month HIIT program to a 12\u2010month lifestyle intervention in children and adolescents with overweight or obesity increased MVPA at 3\u2009months, but not at 12\u2009months. The inverse correlation between changes in vigorous\u2010intensity PA and changes in BMI\n                    <jats:italic>z<\/jats:italic>\n                    \u2010scores underscores the potential of incorporating vigorous\u2010intensity activities into obesity treatment programs.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Trial Registration:<\/jats:bold>\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">ClinicalTrials.gov<\/jats:ext-link>\n                    : NCT05465057\n                  <\/jats:p>","DOI":"10.1111\/sms.70185","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T18:16:18Z","timestamp":1767032178000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Adding High\u2010Intensity Interval Training to a Multidisciplinary Lifestyle Intervention for Childhood Obesity: Secondary Analysis of a Randomized Controlled Trial to Examine the Effects on Physical Activity Behavior"],"prefix":"10.1111","volume":"36","author":[{"given":"Charlotte N\u00f8rkj\u00e6r","family":"Eggertsen","sequence":"first","affiliation":[{"name":"Department of Pediatrics and Adolescent Medicine Aalborg University Hospital  Aalborg Denmark"},{"name":"Steno Diabetes Center North Denmark Aalborg University Hospital  Aalborg Denmark"},{"name":"Department of Clinical Medicine Aalborg University  Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4263-1815","authenticated-orcid":false,"given":"Esben Thyssen","family":"Vestergaard","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Adolescent Medicine Aarhus University Hospital  Aarhus Denmark"},{"name":"Department of Clinical Medicine Aarhus University  Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6645-3596","authenticated-orcid":false,"given":"Morten Bilde","family":"Simonsen","sequence":"additional","affiliation":[{"name":"Center for Mathematical Modelling of Knee Osteoarthritis Aalborg University  Aalborg Denmark"},{"name":"Department of Materials and Production Aalborg University  Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tine Caroc","family":"Warner","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Adolescent Medicine Aalborg University Hospital  Aalborg Denmark"},{"name":"Department of Clinical Medicine Aalborg University  Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens Br\u00f8ndum","family":"Fr\u00f8kj\u00e6r","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Aalborg University  Aalborg Denmark"},{"name":"Department of Radiology Aalborg University Hospital  Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aase","family":"Handberg","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Aalborg University  Aalborg Denmark"},{"name":"Department of Clinical Biochemistry Aalborg University Hospital  Aalborg Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Line Gr\u00f8nholt","family":"Olesen","sequence":"additional","affiliation":[{"name":"Steno Diabetes Center Aarhus Aarhus University Hospital  Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anders","family":"Gr\u00f8ntved","sequence":"additional","affiliation":[{"name":"Research Unit for Exercise Epidemiology, Department of Sports Science and Clinical Biomechanics, Centre of Research in Childhood Health University of Southern Denmark  Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne 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