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EIB is prevalent among elite athletes and individuals exposed to environmental triggers such as cold air and pollutants. Analyzing data from 10 systematic reviews, including 8 meta\u2010analyses, evidence confirms the efficacy of treatments including\n                    <jats:italic>\u03b2<\/jats:italic>\n                    <jats:sub>\n                      <jats:italic>2<\/jats:italic>\n                    <\/jats:sub>\n                    \u2010adrenoceptor (AR) agonists, muscarinic antagonists, inhaled corticosteroids (ICS), leukotriene receptor antagonists (LTRA), and mast\u2010cell stabilizers.\n                    <jats:italic>\u03b2<\/jats:italic>\n                    <jats:sub>\n                      <jats:italic>2<\/jats:italic>\n                    <\/jats:sub>\n                    \u2010AR agonists demonstrate significant protective effects despite concerns regarding long\u2010term use, while combination therapies with ICS and LTRA provide additional benefits. A key proposal is the terminological distinction between EIB and \u201cExercise\u2010Induced Asthma ATtack\u201d (EIAAT), advocating for the use of EIAAT to identify asthma exacerbations during exercise in asthmatics and EIB characterized by bronchospasm in non\u2010asthmatics, thus avoiding misdiagnosis in athletes and guiding appropriate management. The review highlights the promising role of ICS\/formoterol in pre\u2010exercise, as\u2010needed, and Single Maintenance and Reliever Therapy (SMART) regimens, emphasizing the need for randomized controlled trials in athletes with EIB and EIAAT. Ensuring appropriate therapy access while maintaining integrity in competitive sports is pivotal, especially with evolving pharmacological options and anti\u2010doping regulations.\n                  <\/jats:p>","DOI":"10.1111\/sms.70196","type":"journal-article","created":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T14:50:12Z","timestamp":1767451812000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pharmacological Advances in Managing Exercise\u2010Induced Bronchospasm: An Umbrella Review Following\n                    <scp>PRIOR<\/scp>\n                    Guideline"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0456-069X","authenticated-orcid":false,"given":"Luigino","family":"Calzetta","sequence":"first","affiliation":[{"name":"Unit of Respiratory Clinical Pharmacology, Department of Clinical Science and Translational Medicine University of Rome \u201cTor 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