{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:51:15Z","timestamp":1791197475754,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,5,5]],"date-time":"2013-05-05T00:00:00Z","timestamp":1367712000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Ageing of the skin, being chronological or sun induced is highly documented. Scalp, as a specific skin site, has, however, received little attention. This work attempted to describe functional and structural alterations that occur in scalp skin with ageing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two different age groups (N\u00a0=\u00a015 each; 30\u00a0\u00b1\u00a03 and 62\u00a0\u00b1\u00a02 y.o. respectively) of Caucasian women participated in the study. Some functional parameters (<jats:styled-content style=\"fixed-case\">TEWL<\/jats:styled-content>, Sebum level, Hydration, T\u00b0) were recorded on the vertex part of the scalp, after having cut the hair flat on the scalp surface. Imaging of some structural criteria was carried out using high\u2010frequency ultrasound technique and optical coherence tomography on the same scalp site and on the mid\u2010forehead, as a close control skin site.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>As compared with the younger group, the scalp of older women significantly showed a decreased <jats:styled-content style=\"fixed-case\">TEWL<\/jats:styled-content> and a slightly lower T\u00b0. The thickness of total skin (epidermis\u00a0+\u00a0dermis) increased with age on both scalp and on forehead. The thickness of scalp epidermis decreased with age while not significantly altered on forehead. Pseudoattenuation of ultrasound images increased in the older age group. Other criteria, such as sebum level, stratum corneum hydration, stratum corneum thickness, were not found altered with age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>With ageing, some few functional and structural changes are observed in the scalp of Caucasian women. Similarities or differences with those previously reported in other skin sites are discussed.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.12057","type":"journal-article","created":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T01:50:46Z","timestamp":1367805046000},"page":"384-393","source":"Crossref","is-referenced-by-count":31,"title":["Functional and structural age\u2010related changes in the scalp skin of Caucasian women"],"prefix":"10.1111","volume":"19","author":[{"given":"Florence","family":"Pouradier","sequence":"first","affiliation":[{"name":"L'Oreal Research and Innovation Saint\u2010Ouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornillon","family":"C\u00e9line","sequence":"additional","affiliation":[{"name":"L'Oreal Research and Innovation Chevilly\u2010Larue France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D'arras","family":"Marie\u2010Florence","sequence":"additional","affiliation":[{"name":"L'Oreal Research and 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