{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T05:49:34Z","timestamp":1696225774763},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,6,10]],"date-time":"2013-06-10T00:00:00Z","timestamp":1370822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>The purpose of this study was to test the hypothesis that regardless of human skin phototype, areas of depigmented skin, as seen in vitiligo, are optically indistinguishable among skin phototypes. The average of the depigmented skin measurements can be used to develop the base color of realistic prostheses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Materials<\/jats:title><jats:p>Data was analyzed from 20 of 32 recruited vitiligo study participants. Diffuse reflectance spectroscopy measurements were made from depigmented skin and adjacent pigmented skin, then compared with 66 pigmented polydimethylsiloxane phantoms to determine pigment concentrations in turbid media for making realistic facial prostheses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The Area Under spectral intensity Curve (<jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content>) was calculated for average spectroscopy measurements of pigmented sites in relation to skin phototype (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.0505) and depigmented skin in relation to skin phototype (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.59). No significant relationship exists between skin phototypes and depigmented skin spectroscopy measurements. The average of the depigmented skin measurements (<jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content> 19,129) was the closest match to phantom 6.4 (<jats:styled-content style=\"fixed-case\">AUC<\/jats:styled-content> 19,162).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Areas of depigmented skin are visibly indistinguishable per skin phototype, yet spectrometry shows that depigmented skin measurements varied and were unrelated to skin phototype. Possible sources of optical variation of depigmented skin include age, body site, blood flow, quantity\/quality of collagen, and other chromophores. The average of all depigmented skin measurements can be used to derive the pigment composition and concentration for realistic facial prostheses.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.12080","type":"journal-article","created":{"date-parts":[[2013,6,10]],"date-time":"2013-06-10T14:44:55Z","timestamp":1370875495000},"page":"37-42","source":"Crossref","is-referenced-by-count":2,"title":["Depigmented skin and phantom color measurements for realistic prostheses"],"prefix":"10.1111","volume":"20","author":[{"given":"Paul","family":"Tanner","sequence":"first","affiliation":[{"name":"Huntsman Cancer Institute University of Utah Salt Lake City UT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sancy","family":"Leachman","sequence":"additional","affiliation":[{"name":"Department of Dermatology Huntsman Cancer Institute University of Utah Salt Lake City UT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth","family":"Boucher","sequence":"additional","affiliation":[{"name":"Department of Oncological Sciences Cancer Biostatistics Section Huntsman Cancer Institute University of Utah Salt Lake City UT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tun\u00e7er Burak","family":"Oz\u00e7elik","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics Ba\u015fkent University Adana Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,6,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0749.1988.tb00419.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12479191"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197210000-00003"},{"key":"e_1_2_6_5_1","first-page":"3","article-title":"Maxillofacial prosthetics: its origin and present status","volume":"39","author":"Bulbulian AH","year":"1964","journal-title":"Mayo Clin Proc"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(80)90463-1"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2012.2203306"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.2240972"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.201000078"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3913(69)90295-9"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345810600061301"},{"key":"e_1_2_6_12_1","first-page":"85","article-title":"Spectrophotometry and formulations for coloring facial prosthetic silicone elastomer: a pilot clinical trial","volume":"2","author":"Troppman R","year":"1996","journal-title":"J Facial Somato Pros"},{"key":"e_1_2_6_13_1","first-page":"7","article-title":"The use of light remittance measurements to determine intrinsic pigment concentrations in designing a realistic auricular prosthesis","volume":"2","author":"Tanner PB","year":"2008","journal-title":"Int J Anaplastol"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345960750020401"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-849X.1998.tb00212.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-849X.2007.00288.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12275011"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3913(78)80051-1"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2001.01285.x"}],"container-title":["Skin Research and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsrt.12080","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/srt.12080","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T15:42:24Z","timestamp":1696174944000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/srt.12080"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,10]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["10.1111\/srt.12080"],"URL":"https:\/\/doi.org\/10.1111\/srt.12080","archive":["Portico"],"relation":{},"ISSN":["0909-752X","1600-0846"],"issn-type":[{"value":"0909-752X","type":"print"},{"value":"1600-0846","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,10]]}}}