{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T21:09:23Z","timestamp":1778015363330,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,9,4]],"date-time":"2013-09-04T00:00:00Z","timestamp":1378252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Skin cleansers for occupational use are manufactured for different types and degrees of soiling without common, legally binding requirements for product testing. This leads to different, manufacturer\u2010specific test methods and a lack of comparable information on skin cleansing products.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this investigation was to validate a newly developed standardized automated cleansing device (<jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>iD) for <jats:italic>in vivo<\/jats:italic> evaluation of industrial skin cleansers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>iD were tested regarding the intra\u2010 and inter\u2010device specific reproducibility of test results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Skin cleansing process carried out by the three independent washing modules which constitute an <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>iD\u2010unit and two separate <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>iD\u2010units led to highly comparable results. There was no significant difference between the washing modules or between the two separate ACiD\u2010units detected. Only different parameter settings resulted in significantly different detergency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Intra\u2010 and inter\u2010device specific test results of an <jats:italic>in vivo<\/jats:italic> model of skin cleansing using the automated cleansing device (<jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>iD) were reproducible. The long\u2010term aim is a standardized classification of occupational skin cleansing products comparing their skin cleansing effectiveness in relation to their skin irritancy. This might then provide the basis for a rational specific product selection by consumers and may be used as a tool for future product development by manufacturers.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.12113","type":"journal-article","created":{"date-parts":[[2013,9,4]],"date-time":"2013-09-04T13:52:54Z","timestamp":1378302774000},"page":"239-245","source":"Crossref","is-referenced-by-count":15,"title":["Standardization of skin cleansing <i>in vivo<\/i>: part <scp>II<\/scp>. Validation of a newly developed Automated Cleansing Device (<scp>AC<\/scp>iD)"],"prefix":"10.1111","volume":"20","author":[{"given":"F. K.","family":"Sonsmann","sequence":"first","affiliation":[{"name":"Department of Occupational Dermatology Environmental Medicine and Health Theory University of Osnabr\u00fcck Osnabr\u00fcck Germany"},{"name":"iDerm \u2010 Institute for Interdisciplinary Dermatological Prevention and Rehabilitation University of Osnabr\u00fcck Osnabr\u00fcck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Strunk","sequence":"additional","affiliation":[{"name":"Department of Occupational Dermatology Environmental Medicine and Health Theory University of Osnabr\u00fcck Osnabr\u00fcck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Gediga","sequence":"additional","affiliation":[{"name":"iDerm \u2010 Institute for Interdisciplinary Dermatological Prevention and Rehabilitation University of Osnabr\u00fcck Osnabr\u00fcck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Schliemann","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Jena Jena Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Seyfarth","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Jena Jena Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Elsner","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Jena Jena Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. L.","family":"Diepgen","sequence":"additional","affiliation":[{"name":"Department of Social Medicine, Occupational and Environmental Dermatology University of Heidelberg Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Kutz","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Technology Hochschule Ostwestfalen\u2010Lippe \u2010 University of Applied Sciences Lemgo Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. M.","family":"John","sequence":"additional","affiliation":[{"name":"Department of Occupational Dermatology Environmental Medicine and Health Theory University of Osnabr\u00fcck Osnabr\u00fcck Germany"},{"name":"iDerm \u2010 Institute for Interdisciplinary Dermatological Prevention and Rehabilitation University of Osnabr\u00fcck Osnabr\u00fcck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,4]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Regulation (EC) No 1223\/2009 of the European parliament and of the council of 30 November 2009 on cosmetic products 2009. Available at:http:\/\/eur-lex.europa.eu\/LexUriServ\/LexUriServ.do?uri=OJ:L:2009:342:0059:0209:en:PDF(last accessed 11 May 2013)"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2010.07468_supp.x"},{"key":"e_1_2_10_4_1","article-title":"Standardization of skin cleaning in\u2010vivo: part I. 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