{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:25:37Z","timestamp":1779236737320,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,5,24]],"date-time":"2014-05-24T00:00:00Z","timestamp":1400889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The non\u2010contact optical methods phaseshift rapid <jats:italic>in vivo<\/jats:italic> measurement of skin (<jats:styled-content style=\"fixed-case\">PRIMOS<\/jats:styled-content>) and surface evaluation of living skin (<jats:styled-content style=\"fixed-case\">SELS<\/jats:styled-content>) are widely applied for measuring skin surface topography. The aims of the present study were to evaluate reliability and validity of these methods and to compare skin roughness intraindividually.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">SELS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PRIMOS<\/jats:styled-content> measurements were performed on four skin areas of the left and right volar forearms in 12 healthy elderly subjects. Reliability and correlations were analyzed for Visioscan<jats:sup>\u00ae<\/jats:sup> and <jats:styled-content style=\"fixed-case\">PRIMOS<\/jats:styled-content> roughness parameters. Student's <jats:italic>t<\/jats:italic>\u2010tests for estimating differences between contralateral volar forearm sites were applied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">ICC<\/jats:styled-content> coefficients of the Visioscan<jats:sup>\u00ae<\/jats:sup> roughness estimates ranged between 0.50 and 0.95 and of the <jats:styled-content style=\"fixed-case\">PRIMOS<\/jats:styled-content> measurements between 0.01 and 1.00. The Visioscan<jats:sup>\u00ae<\/jats:sup> parameters <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content>r, <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content>sm, Rmax, and Rz, and the <jats:styled-content style=\"fixed-case\">PRIMOS<\/jats:styled-content> parameters Ra, Rz, Smax, Wt, and Sz showed most significant correlations with each other and to additional roughness parameters. Mean roughness differences between contralateral forearm skin areas ranged between 0.0 (<jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content>sc) and 6.7 (Rmax).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The Visioscan<jats:sup>\u00ae<\/jats:sup> parameters <jats:styled-content style=\"fixed-case\">SE<\/jats:styled-content>r, Rmax, and Rz showed most reliable and valid values and were largely comparable on contralateral forearm skin sites in elderly subjects. Rmax, Rz, and Ra should be preferred for measuring skin surface topography with <jats:styled-content style=\"fixed-case\">PRIMOS<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.12156","type":"journal-article","created":{"date-parts":[[2014,5,24]],"date-time":"2014-05-24T07:53:04Z","timestamp":1400917984000},"page":"54-60","source":"Crossref","is-referenced-by-count":30,"title":["Reliability and validity of two <i>in vivo<\/i> measurements for skin surface topography in aged adults"],"prefix":"10.1111","volume":"21","author":[{"given":"C.","family":"Trojahn","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy Clinical Research Center for Hair and Skin Science Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Schario","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Clinical Research Center for Hair and Skin Science Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Dobos","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Clinical Research Center for Hair and Skin Science Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Blume\u2010Peytavi","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Clinical Research Center for Hair and Skin Science Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Kottner","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Clinical Research Center for Hair and Skin Science Charit\u00e9\u2010Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,5,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2013.04.008"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.12119."},{"key":"e_1_2_7_4_1","first-page":"315","article-title":"\u2018Dry\u2019 skin in atopic dermatitis. 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