{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,11]],"date-time":"2026-01-11T10:10:22Z","timestamp":1768126222215,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,6,7]],"date-time":"2015-06-07T00:00:00Z","timestamp":1433635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background\/purpose<\/jats:title><jats:p>The importance of water in human physiology is well known, also for skin functionality. This study was conducted to assess the effects of dietary water on epidermal skin hydration in healthy females.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010four healthy females (mean 24.5 \u00b1 6.34 years old) were selected and characterized according to their dietary daily habits, by a previously validated Food Frequency Questionnaire. For 1\u00a0month, these subjects were asked to add 2\u00a0L\/day of water to their regular dietary habits. Measurements took place at day D0, D15, and D30, and involved general variables (body weight, blood pressure, Body Mass Index) and specific skin physiological variables in five anatomical sites (ventral forearm, anterior leg, dorsal hand, zygomatic area, and forehead) involving epidermal superficial and deep hydration, by capacitance and transepidermal water loss (<jats:styled-content style=\"fixed-case\">TEWL<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This water overload (2\u00a0L\/day\/30\u00a0days) did not change the blood volume or weight of the individuals. However, both superficial and deep skin hydration were clearly in those individuals that regularly consumed lees water per day. No significant effect was observed in the <jats:styled-content style=\"fixed-case\">TEWL<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study clearly suggests that dietary water intake seems to influence skin water content. Nevertheless further <jats:italic>in vivo<\/jats:italic> investigations involving other variables, such as biomechanical descriptors, should follow to look deeper into this aspect of skin physiology.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.12208","type":"journal-article","created":{"date-parts":[[2015,6,11]],"date-time":"2015-06-11T01:30:20Z","timestamp":1433986220000},"page":"413-418","source":"Crossref","is-referenced-by-count":14,"title":["Positive impact of dietary water on <i>in vivo<\/i> epidermal water physiology"],"prefix":"10.1111","volume":"21","author":[{"given":"M. L.","family":"Palma","sequence":"first","affiliation":[{"name":"CBIOS \u2013 Research Centre Biosciences and Health Technologies Universidade Lus\u00f3fona Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Tavares","sequence":"additional","affiliation":[{"name":"CBIOS \u2013 Research Centre Biosciences and Health Technologies Universidade Lus\u00f3fona Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. W.","family":"Fluhr","sequence":"additional","affiliation":[{"name":"Department of Dermatology Charit\u00e9 University Clinic Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. J.","family":"Bujan","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Universitad de Alcal\u00e1 Henares Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. M.","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"CBIOS \u2013 Research Centre Biosciences and Health Technologies Universidade Lus\u00f3fona Lisboa Portugal"},{"name":"Pharmacological Sciences Department Faculty of Pharmacy University of Lisbon Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1999.00532.x"},{"key":"e_1_2_7_3_1","volume-title":"Guyton and Hall textbook of medical physiology","author":"Hall JE","year":"2010"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2009.111"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.2010.00304.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700994"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000080218"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000324051"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/gln045"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0909-752X.2006.00160.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00501.2004"},{"key":"e_1_2_7_12_1","unstructured":"2010 U.S. Government Printing Office 2010 Washington DC"},{"key":"e_1_2_7_13_1","first-page":"1459","article-title":"EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA); Scientific Opinion on dietary reference values for water","volume":"8","author":"Panel E","year":"2010","journal-title":"EFSA J"},{"key":"e_1_2_7_14_1","first-page":"412","article-title":"Validade Relativa de um question\u00e1rio de frequ\u00eancia alimentar atrav\u00e9s da compara\u00e7\u00e3o de um registo alimentar de quatro dias","volume":"16","author":"Moreira P","year":"2003","journal-title":"Acta Med Port"},{"key":"e_1_2_7_15_1","unstructured":"PalmaL TavaresL BujanMRL.Diet Related Water Seems To Affect In Vivo Skin Hydration and Biomechanics [Internet]. 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