{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T18:24:41Z","timestamp":1773858281750,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,1,25]],"date-time":"2016-01-25T00:00:00Z","timestamp":1453680000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2016,11]]},"abstract":"Purpose<\/jats:title>To compare the diagnostic imaging ability of three different optical coherence tomography (OCT<\/jats:styled-content>) devices in non\u2010melanoma skin cancer (NMSC<\/jats:styled-content>).<\/jats:p><\/jats:sec>Methods<\/jats:title>Thirty actinic keratoses (AK<\/jats:styled-content>s) and 27 basal cell carcinomas (BCC<\/jats:styled-content>s) of 29 patients were examined with three different OCT<\/jats:styled-content> devices, VivoSight\u00ae<\/jats:sup>, Callisto\u00ae<\/jats:sup> and Skintell\u00ae<\/jats:sup>.<\/jats:p><\/jats:sec>Results<\/jats:title>Complete data sets were available for 16 BCC<\/jats:styled-content>s and 10 AK<\/jats:styled-content>s of 18 patients. All OCT<\/jats:styled-content> devices were able to discriminate BCC<\/jats:styled-content>s and AK<\/jats:styled-content>s significantly from perilesional normal skin due to lower signal intensities as well as a thicker stratum corneum and epidermis in AK<\/jats:styled-content>s. A significant decrease in the signal intensity and thickness of all skin layers was noted with Skintell\u00ae<\/jats:sup> in contrast to VivoSight\u00ae<\/jats:sup> and Callisto\u00ae<\/jats:sup>. OCT<\/jats:styled-content> comparisons revealed only slight differences between VivoSight\u00ae<\/jats:sup> and Callisto\u00ae<\/jats:sup>. Regarding BCC<\/jats:styled-content> tumor thickness VivoSight\u00ae<\/jats:sup> and Callisto\u00ae<\/jats:sup> correlated well, histology did not correlate with the three OCT<\/jats:styled-content> devices, whereas Skintell\u00ae<\/jats:sup> showed no correlation with VivoSight\u00ae<\/jats:sup>, Callisto\u00ae<\/jats:sup> or histology.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>All tested OCT<\/jats:styled-content> devices could identify BCC<\/jats:styled-content>s and AK<\/jats:styled-content>s objectively through standardized measurement of signal intensity and skin layer thickness. Due to their technical specifications (resolution, penetration depth), each of the OCT<\/jats:styled-content> systems offers additional and special information on NMSC<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.12277","type":"journal-article","created":{"date-parts":[[2016,1,25]],"date-time":"2016-01-25T10:43:00Z","timestamp":1453718580000},"page":"395-405","source":"Crossref","is-referenced-by-count":20,"title":["Comparison of different optical coherence tomography devices for diagnosis of non\u2010melanoma skin cancer"],"prefix":"10.1111","volume":"22","author":[{"given":"S.","family":"Schuh","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergology General Hospital Augsburg Augsburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Kaestle","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology General Hospital Augsburg Augsburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Sattler","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology Ludwig\u2010Maximilian University of Munich Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Welzel","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology General Hospital Augsburg Augsburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,1,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1364\/OL.13.000186"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2002.800510.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.18.6.061224"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2013.11.003"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/153303460300200605"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20573"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2006.11.012"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1142\/S1793545816500036"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-24163-5_101"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12797"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11202.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000343770"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0846.2012.00626.x"},{"key":"e_1_2_6_15_1","unstructured":"Michelson Diagnostics.VivoSight OCT Scanner\u2010 Technical Specification. 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