{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T15:38:03Z","timestamp":1770565083764,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,8,11]],"date-time":"2016-08-11T00:00:00Z","timestamp":1470873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:sec><jats:title>Background\/purpose<\/jats:title><jats:p>Treatment of atopic dermatitis (<jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>) and psoriasis requires their differentiation from other eczematoid dermatitis and a determination of disease severity. However, both can be clinically difficult and the findings subjectively interpreted. We investigated the utility of <jats:italic>in vivo<\/jats:italic> autofluorescence (<jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>) measurements for diagnosis of both diseases, and determination of severity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Thirty patients with <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> and 30 with psoriasis were recruited, together with sex\u2010 and age\u2010matched patients with healthy skin. <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> intensity was measured using the EcoSkin<jats:sup>\u00ae<\/jats:sup> fluorescence video dermatoscope. In <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> and psoriasis patients, <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> in non\u2010sun\u2010exposed lesional and non\u2010lesional skin was measured. To identify the locations that reflect characteristics of <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> AF<\/jats:styled-content> was also measured at the other sites in the patients with <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> was associated with lower <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> and psoriasis with higher <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> intensity peaking around 620 nm. In addition, skin <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content> intensity of each disease was associated with severity of lesion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Non\u2010invasive measurement of skin <jats:styled-content style=\"fixed-case\">AF <\/jats:styled-content><jats:italic>in vivo<\/jats:italic> can aid in diagnosis of <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> and psoriasis as well as in treatment monitoring.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.12315","type":"journal-article","created":{"date-parts":[[2016,8,11]],"date-time":"2016-08-11T06:37:03Z","timestamp":1470897423000},"page":"169-175","source":"Crossref","is-referenced-by-count":6,"title":["Comparative study of skin autofluorescence expression in atopic dermatitis and psoriasis: A prospective <i>in vivo<\/i> study"],"prefix":"10.1111","volume":"23","author":[{"given":"J. H.","family":"Yim","sequence":"first","affiliation":[{"name":"Department of Dermatology College of Medicaine Kyung Hee University Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. H.","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Dermatology College of Medicaine Kyung Hee University Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. K.","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Dermatology College of Medicaine Kyung Hee University Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,8,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.6.3262"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(99)70536-1"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2000.106484"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0560.2001.280201.x"},{"key":"e_1_2_8_6_1","first-page":"542","article-title":"The coexistence of atopic dermatitis and psoriasis in a 12 months\u2010old girl","volume":"19","author":"Kamer B","year":"2005","journal-title":"Pol Merkur Lekarski"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1364\/OE.8.000002"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1364\/OE.18.007857"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1529\/biophysj.106.099457"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.2.003295"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2011.12.009"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.200710022"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2008.00815.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.201300124"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.200910062"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2011.01405.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12458"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.446"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13671-013-0066-6"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1974.01630100087033"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.1998.00345.x"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.1999.00799.x"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9101(1997)20:3<319::AID-LSM11>3.0.CO;2-8"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01262327"}],"container-title":["Skin Research and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsrt.12315","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsrt.12315","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/srt.12315","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T01:44:12Z","timestamp":1696211052000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/srt.12315"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,11]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1111\/srt.12315"],"URL":"https:\/\/doi.org\/10.1111\/srt.12315","archive":["Portico"],"relation":{},"ISSN":["0909-752X","1600-0846"],"issn-type":[{"value":"0909-752X","type":"print"},{"value":"1600-0846","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,11]]}}}