{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T16:08:39Z","timestamp":1779206919006,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,8,12]],"date-time":"2016-08-12T00:00:00Z","timestamp":1470960000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004085","name":"Ministry of Education, Science and Technology","doi-asserted-by":"publisher","award":["NRF\u20102014R1A1 A2058341"],"award-info":[{"award-number":["NRF\u20102014R1A1 A2058341"]}],"id":[{"id":"10.13039\/501100004085","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["NRF\u20102016R1C1B1016492"],"award-info":[{"award-number":["NRF\u20102016R1C1B1016492"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Rosacea is a common chronic inflammatory disorder affecting facial skin. Currently, no accurate and objective method is available for assessing the severity of rosacea. Most studies use the National Rosacea Society Standard (<jats:styled-content style=\"fixed-case\">NRSS<\/jats:styled-content>) grading method, which lacks objectivity and yields varying results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighteen patients with rosacea were included. Clinical severity was assessed on the basis of the <jats:styled-content style=\"fixed-case\">NRSS<\/jats:styled-content> grade, Investigators' Global Assessment, Patients' Global Assessment, and Dermatology Quality of Life Index. A skin color analysis system was used to measure the facial area showing erythema, and biophysical parameters of facial skin (transepidermal water loss and skin surface hydration) were examined. To find statistical significant in classification severity of the rosacea, statistical analysis was performed with all parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A significant correlation (<jats:italic>P<\/jats:italic> &lt; 0.05) was found between the <jats:styled-content style=\"fixed-case\">NRSS<\/jats:styled-content> grade, facial area showing erythema, and biophysical parameters. The latter two factors differed significantly among patients with rosacea of different levels of severity (mild, moderate, severe; <jats:italic>P<\/jats:italic> &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Color imaging systems can be useful and reliable for evaluating the severity of rosacea, in addition to biophysical parameter assessment. The combination of these two analytical methods enabled objective and quantitative evaluation of the severity of rosacea.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.12318","type":"journal-article","created":{"date-parts":[[2016,8,12]],"date-time":"2016-08-12T05:06:48Z","timestamp":1470978408000},"page":"186-193","source":"Crossref","is-referenced-by-count":15,"title":["Clinical assessment of rosacea severity: oriental score vs. quantitative assessment method with imaging and biomedical tools"],"prefix":"10.1111","volume":"23","author":[{"given":"J.","family":"Kim","sequence":"first","affiliation":[{"name":"Research Institute for Skin Imaging Korea University Medical School Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. W.","family":"Ahn","sequence":"additional","affiliation":[{"name":"Research Institute for Skin Imaging Korea University Medical School Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ha","sequence":"additional","affiliation":[{"name":"Department of Nursing School of Health Chungbuk Health and Science University Chungbuk Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. H.","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Dermatology Korea University Medical School Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Medical IT Engineering College of Medical Sciences Soonchunhyang University Chungnam Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Oh","sequence":"additional","affiliation":[{"name":"Research Institute for Skin Imaging Korea University Medical School Seoul Korea"},{"name":"Department of Dermatology Korea University Medical School Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,8,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.120625"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2003.01817.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1970"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fsc.2012.11.004"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp042829"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.02.1121"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2004.01.048"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.01.010"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1159\/000056341"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1473-2165.2008.00355.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.32.12.1461"},{"key":"e_1_2_7_13_1","first-page":"1","article-title":"A quantitative study of nanoparticle skin penetration with interactive segmentation","author":"Lee O","year":"2015","journal-title":"Med Biol Eng Compu"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12522"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2011.05176.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.05985.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12770"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2537"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12251"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.08.006"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2010.03.002"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2002.00497.x"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230X-13-104"}],"container-title":["Skin Research and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsrt.12318","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsrt.12318","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/srt.12318","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T01:44:48Z","timestamp":1696211088000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/srt.12318"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,12]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1111\/srt.12318"],"URL":"https:\/\/doi.org\/10.1111\/srt.12318","archive":["Portico"],"relation":{},"ISSN":["0909-752X","1600-0846"],"issn-type":[{"value":"0909-752X","type":"print"},{"value":"1600-0846","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,12]]}}}