{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T16:29:19Z","timestamp":1792081759866,"version":"4.4.0"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,10,22]],"date-time":"2017-10-22T00:00:00Z","timestamp":1508630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Validated tools are essential to evaluate facial skin aging for both dermatological and cosmetic investigations. While many visual aging scales have been developed, few have been validated and none in terms of degree of distinguishability (<jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content>). We developed and validated a series of visual scales using a novel digital interface for scoring facial skin aging in Caucasian women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>Three dermatologists independently established scales for 12 distinct aging signs from high\u2010definition facial photographs of 400 adult women (Fitzpatrick phototypes I\u2010<jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content>) taken under standardized conditions. They then selected a consensus scale for each individual sign with a representative photo per grade. Scales were integrated into a digital interface allowing simultaneous viewing of all grades of each scale alongside the photograph of a test subject. Next, scales were validated by a different dermatologist, a general practitioner and a non\u2010medical expert skin evaluator using photos of 350 women which had not been used for establishing the scales.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Kappa estimates showed almost perfect agreement for wrinkle and skin aging scales (\u22650.85) and moderate to substantial agreement for scales relating to color irregularities (telangiectasia, solar lentigines, freckles) for both inter\u2010 and intra\u2010observer reproducibility. Intra\u2010observer <jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content> estimates were mostly high. Non\u2010dermatologists performed well on reproducibility for both Kappa (from 0.6 to 0.9) and <jats:styled-content style=\"fixed-case\">DD<\/jats:styled-content> estimates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our work demonstrates that the digital interface scales for 12 distinct aging features are highly suitable for use in clinical and epidemiological studies on skin aging by both dermatologists and non\u2010dermatologists.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.12413","type":"journal-article","created":{"date-parts":[[2017,10,23]],"date-time":"2017-10-23T04:16:52Z","timestamp":1508732212000},"page":"196-202","source":"Crossref","is-referenced-by-count":11,"title":["Validation of digital photographic reference scales for evaluating facial aging signs"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0465-2474","authenticated-orcid":false,"given":"Randa","family":"Jdid","sequence":"first","affiliation":[{"name":"Department of Biology &amp; Women's Beauty Chanel  Pantin France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Latreille","sequence":"additional","affiliation":[{"name":"Department of Biology &amp; Women's Beauty Chanel  Pantin France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9rique","family":"Soppelsa","sequence":"additional","affiliation":[{"name":"Department of Biometrics Lincoln  Boulogne Billancourt France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erwin","family":"Tschachler","sequence":"additional","affiliation":[{"name":"CE.R.I.E.S.  Neuilly sur Seine France"},{"name":"Department of Dermatology Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9rique","family":"Morizot","sequence":"additional","affiliation":[{"name":"Department of Biology &amp; Women's Beauty Chanel  Pantin France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,10,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/14764172.2010.514920"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.458"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.381"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-013-1374-4"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms5020"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2015.62"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1992.01680130061006"},{"key":"e_1_2_6_9_1","volume-title":"Skin aging atlas. 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