{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T07:52:35Z","timestamp":1740124355804,"version":"3.37.3"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,2,15]],"date-time":"2018-02-15T00:00:00Z","timestamp":1518652800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background\/purpose<\/jats:title><jats:p>The aim of this study was to measure lentigines' pigmentation over a long period of time and evaluate if summer over\u2010pigmentation can be avoided by the use a <jats:styled-content style=\"fixed-case\">SPF<\/jats:styled-content>30 day skin cream.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seventeen healthy female volunteers aged 50 and over and presenting lentigines participated in the study from spring to summer. Throughout the study, all subjects applied a <jats:styled-content style=\"fixed-case\">SPF<\/jats:styled-content>30 daily skin cream to only one hand. Color measurements of the target lesions were performed with a chromameter and with a color\u2010calibrated camera. Target lesions were also imaged with in vivo reflectance confocal microscopy (<jats:styled-content style=\"fixed-case\">RCM<\/jats:styled-content>). A specific procedure for re\u2010registering the images was developed to ensure that the same papillae were measured over time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both color measurement methods, chromametry and color\u2010calibrated camera, showed that lentigines treated over time with the <jats:styled-content style=\"fixed-case\">SPF<\/jats:styled-content>30 day skin cream were significantly lighter than the non\u2010treated lentigines. The <jats:styled-content style=\"fixed-case\">RCM<\/jats:styled-content> images showed a decrease in the papillary contrast for the treated lentigines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study shows that this over\u2010pigmentation can be avoided using a <jats:styled-content style=\"fixed-case\">SPF<\/jats:styled-content>30 day skin cream. Moreover, we have demonstrated that very fine re\u2010registration of the <jats:styled-content style=\"fixed-case\">RCM<\/jats:styled-content> images is possible and ensures a more robust analysis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.12458","type":"journal-article","created":{"date-parts":[[2018,2,15]],"date-time":"2018-02-15T05:12:54Z","timestamp":1518671574000},"page":"485-489","source":"Crossref","is-referenced-by-count":4,"title":["Protection against summer solar lentigo over\u2010pigmentation with a <scp>SPF<\/scp>30 daily cream"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3375-5226","authenticated-orcid":false,"given":"G.","family":"Josse","sequence":"first","affiliation":[{"name":"Pierre Fabre Dermo\u2010Cosm\u00e9tique Centre de Recherche sur la Peau  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Le Digabel","sequence":"additional","affiliation":[{"name":"Pierre Fabre Dermo\u2010Cosm\u00e9tique Centre de Recherche sur la Peau  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Questel","sequence":"additional","affiliation":[{"name":"Pierre Fabre Dermo\u2010Cosm\u00e9tique Centre de Recherche sur la Peau  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,2,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1992.tb16989.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1990.tb16121.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(97)80224-1"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2012.01574.x"},{"key":"e_1_2_6_6_1","first-page":"93","article-title":"Chromametric quantification of pigmentary changes in the solar lentigo after sunlight exposure","volume":"10","author":"Adhoute H","year":"1994","journal-title":"Photodermatol Photoimmunol Photomed"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.12182"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12606215"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.03.009"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2012.06.012"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1109\/42.875195"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.1999.00690.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2012.01451.x"},{"volume-title":"R: A Language and Environment for Statistical Computing","year":"2014","author":"R Core Team","key":"e_1_2_6_14_1"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0749.2004.00131.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4PP00332B"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06996.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ics.12016"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07830.x"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.235"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09946.x"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12234"}],"container-title":["Skin Research and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fsrt.12458","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/srt.12458","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/srt.12458","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/srt.12458","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T01:03:25Z","timestamp":1694394205000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/srt.12458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,15]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["10.1111\/srt.12458"],"URL":"https:\/\/doi.org\/10.1111\/srt.12458","archive":["Portico"],"relation":{},"ISSN":["0909-752X","1600-0846"],"issn-type":[{"type":"print","value":"0909-752X"},{"type":"electronic","value":"1600-0846"}],"subject":[],"published":{"date-parts":[[2018,2,15]]}}}