{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T19:53:14Z","timestamp":1788292394300,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T00:00:00Z","timestamp":1569283200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Ultra\u2010High Frequency Ultrasound (<jats:styled-content style=\"fixed-case\">UHFUS<\/jats:styled-content>) is a recently introduced diagnostic technique involving the use of higher frequencies compared to\u00a0conventional ultrasound. Among the several fields of application, intraoral usage of <jats:styled-content style=\"fixed-case\">UHFUS<\/jats:styled-content> appears still limited. We report the intraoral evaluation of Oral Lichen Planus (<jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>) by means of <jats:styled-content style=\"fixed-case\">UHFUS<\/jats:styled-content> and describe typical <jats:styled-content style=\"fixed-case\">UHFUS<\/jats:styled-content> aspect of different forms of presentation of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Patients with clinical and histological diagnosis of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> were enrolled in the study. <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> lesions were evaluated by means of intraoral <jats:styled-content style=\"fixed-case\">UHFUS<\/jats:styled-content> performed at 70\u00a0<jats:styled-content style=\"fixed-case\">MH<\/jats:styled-content>z, using B\u2010mode and C\u2010mode, in order to characterize the echostructure of each form of presentation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty patients in total were enrolled, and <jats:styled-content style=\"fixed-case\">UHFUS<\/jats:styled-content> features were described for different <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> forms. All the lesions showed a thick, hypoechoic superficial layer in the mucosal stratum, suggesting that such <jats:styled-content style=\"fixed-case\">UHFUS<\/jats:styled-content> alteration can be pathognomonic of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Ultra\u2010High Frequency Ultrasound was able to differentiate superficial alterations of the oral mucosa, giving insight on possible applications of <jats:styled-content style=\"fixed-case\">UHFUS<\/jats:styled-content> in the study of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> beyond clinical and histological investigations. Due to a limited study sample, we cannot draw firm conclusions. However, it is reasonable to think that <jats:styled-content style=\"fixed-case\">UHFUS<\/jats:styled-content> evaluation of <jats:styled-content style=\"fixed-case\">OLP<\/jats:styled-content> may provide useful information to the clinician.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.12777","type":"journal-article","created":{"date-parts":[[2019,9,24]],"date-time":"2019-09-24T10:23:02Z","timestamp":1569320582000},"page":"200-204","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Intraoral Ultra\u2010High Frequency Ultrasound study of oral lichen planus: A pictorial review"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4902-7813","authenticated-orcid":false,"given":"Rossana","family":"Izzetti","sequence":"first","affiliation":[{"name":"Department of Translational Research and of New Technologies in Medicine and Surgery University of Pisa Pisa 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