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Intra\u2010rater reliability was assessed by taking three sets of measures on images from 10 people and inter\u2010session reliability by capturing three images, lifting the probe from the skin in between. Methods were adjusted, and repeated images from four sites were taken in people with primary lymphoedema (PLO) and reliability re\u2010assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Intra\u2010rater reliability in NLO and PLO for echogenicity measures were excellent (NLO ICC<jats:sub>(3,1)<\/jats:sub>: .989; PLO .997) across all sites and specific to each site (calf: ICC<jats:sub>(3,1)<\/jats:sub>: .989; and foot: ICC<jats:sub>(3,1)<\/jats:sub>: .999, respectively). Inter\u2010session reliability was moderate for NLO (ICC<jats:sub>(3,1)<\/jats:sub>: .727), improving after method modifications for PLO (ICC<jats:sub>(3,1)<\/jats:sub>: .916). When investigated by site, inter\u2010session reliability was good in the foot (ICC<jats:sub>(3,1)<\/jats:sub>: .811) and moderate in the calf (ICC<jats:sub>(3,1)<\/jats:sub>: .616). Mean thickness analysed by site resulted in good inter\u2010session reliability only in the foot (ICC<jats:sub>(3,1)<\/jats:sub> .838).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Intra\u2010rater reliability was excellent using the DermaScan C for dermal measures in people with primary lymphoedema. Inter\u2010session reliability required particular attention to method and gain settings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.12880","type":"journal-article","created":{"date-parts":[[2020,6,24]],"date-time":"2020-06-24T13:21:45Z","timestamp":1593004905000},"page":"813-823","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Dermal thickness and echogenicity using DermaScan C high frequency ultrasound: Methodology and reliability testing in people with and without primary lymphoedema"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2211-7237","authenticated-orcid":false,"given":"Jane","family":"Phillips","sequence":"first","affiliation":[{"name":"College of Nursing &amp; Health Sciences Caring Futures Institute Flinders University Adelaide SA Australia"},{"name":"Murdoch Children's Research Institute Parkville Vic. 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