{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T02:46:58Z","timestamp":1793933218078,"version":"4.8.0"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T00:00:00Z","timestamp":1603238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Non\u2010invasive diagnostic techniques in dermatology gained increasing popularity in the last decade. Reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) are meanwhile established in research and clinical routine. While OCT is mainly indicated for detecting non\u2010melanoma skin cancer, RCM has proven its usefulness additionally in distinguishing melanocytic lesions. Line\u2010field confocal optical coherence tomography (LC\u2010OCT) is an emerging tool combining the principles of both above\u2010mentioned methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Healthy skin at different body sites and exemplary skin lesions (basal cell carcinoma, malignant melanoma, actinic keratosis) were examined using dermoscopy, RCM, OCT and LC\u2010OCT. Standard features for RCM and OCT and comparable features for LC\u2010OCT were analysed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>LC\u2010OCT has a lower penetration depth but superior resolution compared to OCT. In comparison with RCM, which provides only horizontal sections, LC\u2010OCT creates both vertical and horizontal images in real time and has nearly the same cellular resolution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Our preliminary experiences suggest that LC\u2010OCT combines the advantages of RCM and OCT, with optimal resolution and penetration depth to diagnose all types of skin cancer.<\/jats:p>\n                    <jats:p>Larger systematic studies are needed to further characterize the field of use of this device and its sensitivity and specificity compared to histology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/srt.12949","type":"journal-article","created":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T13:54:51Z","timestamp":1603288491000},"page":"340-352","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":117,"title":["Line\u2010field confocal optical coherence tomography\u2014Practical applications in dermatology and comparison with established imaging methods"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9860-1095","authenticated-orcid":false,"given":"Cristel","family":"Ruini","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital Ludwig Maximilian University Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1470-7619","authenticated-orcid":false,"given":"Sandra","family":"Schuh","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology University Hospital Augsburg Augsburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8677-3028","authenticated-orcid":false,"given":"Elke","family":"Sattler","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital Ludwig Maximilian University Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6099-7418","authenticated-orcid":false,"given":"Julia","family":"Welzel","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology University Hospital Augsburg Augsburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16154"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13853"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD013189"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00347-018-0718-9"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-017-0175-4"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD013191"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2016.05.001"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.10.000694"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1364\/OE.26.033534"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.385303"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.23.10.106007"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.12815"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12606215"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.04.047"}],"container-title":["Skin Research and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/srt.12949","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/srt.12949","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/srt.12949","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T09:39:48Z","timestamp":1693561188000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/srt.12949"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,21]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1111\/srt.12949"],"URL":"https:\/\/doi.org\/10.1111\/srt.12949","archive":["Portico"],"relation":{},"ISSN":["0909-752X","1600-0846"],"issn-type":[{"value":"0909-752X","type":"print"},{"value":"1600-0846","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,21]]},"assertion":[{"value":"2020-06-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}