{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:45:14Z","timestamp":1790729114603,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T00:00:00Z","timestamp":1615334400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Primary cicatricial alopecia is a potentially irreversible process of hair loss, in which for proper diagnosis a skin biopsy is necessary. Searching for new, non\u2010invasive diagnostic methods may shorten the time for final diagnosis, initiating appropriate treatment and reduce the need for biopsy. The aim of this study was to evaluate the usefulness of high\u2010frequency ultrasonography (HF\u2010USG) as a diagnostic method in patients with primary scarring alopecia and to compare it with trichoscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>The study covered a total of 44 adults: 8 with classic lichen planopilaris (LPP), 11 with discoid lupus erythematosus (DLE), 14 with frontal fibrosing alopecia (FFA), and 11 healthy volunteers. Each patient underwent physical and trichoscopic examination which was the base for qualification for active\/inactive stage of the disease. Then, HF\u2010USG was performed using a probe with a frequency of 20\u00a0MHz. In HF\u2010USG images, the following elements were evaluated and measured: entrance echo (EE), follicular structures (FS), dermal background (DB), and dermal\/subdermal border (D\/SB).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Inactive phase was characterized by significantly lower number\/lack of FS compared to the active phase of scarring alopecia. HF\u2010USG of active LPP\/FFA presented cigar\u2010like shaped FS, while inactive stage pronounced D\/SB forming saw\u2010like pattern. Active DLE in HF\u2010USG were associated with focal, doubled EE and widened FS with a tendency to create hypoechogenic wide, structureless bands within the skin. In inactive DLE, there was no specific pattern of D\/SB or rarely puzzle\u2010like pattern.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>HF\u2010USG images differ depending on the phase of the disease and the type of scarring alopecia, similarly to trichoscopic examination.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.13018","type":"journal-article","created":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T08:23:48Z","timestamp":1615364628000},"page":"774-784","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Suitability of high\u2010frequency ultrasonography (20 MHz) in evaluation of various forms of primary cicatricial alopecia in relation to trichoscopy \u2014 pilot study"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7914-8694","authenticated-orcid":false,"given":"Dominik","family":"Mikiel","sequence":"first","affiliation":[{"name":"Department of Dermatology Poznan University of Medical Sciences Poznan Poland"},{"name":"Department of Skin Diseases Provincial Hospital in Poznan Poznan Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9531-7358","authenticated-orcid":false,"given":"Adriana","family":"Pola\u0144ska","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Poznan University of Medical Sciences Poznan Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryszard","family":"\u017baba","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Poznan University of Medical Sciences Poznan 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