{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T21:34:17Z","timestamp":1783200857925,"version":"3.54.6"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,10,29]],"date-time":"2022-10-29T00:00:00Z","timestamp":1667001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82103767"],"award-info":[{"award-number":["82103767"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004829","name":"Department of Science and Technology of Sichuan Province","doi-asserted-by":"publisher","award":["2021YFS0199"],"award-info":[{"award-number":["2021YFS0199"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Hyperpigmentary disorder is one of the commonest skin concerns in dermatology clinics. The availability of noninvasive instruments provided a convenient, objective, and reproducible methodology for the evaluation of pigmentation and skin color. The aim of this study is to compare CSKIN and VISIA in measuring facial hyperpigmentation, as well as to assess the correlation between the instrumental analyzing and clinical evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighty Chinese patients were enrolled. Images were taken and analyzed by VISIA from Canfield and CSKIN from Yanyun Technology, and the facial hyperpigmentation was graded by three dermatologists.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Feature counts within the facial pigmented areas analyzed by VISIA showed positive correlations with brown pixels (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.331, <jats:italic>p<\/jats:italic> &lt;\u00a00.05) and brown percent (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.395, <jats:italic>p<\/jats:italic> &lt;\u00a00.0001) measured by CSKIN. The parameters measured by CSKIN and VISIA were significantly correlated with visual scores graded by the dermatologists, with VISIA presenting a moderate correlation (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.509, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) and CSKIN a slightly stronger correlation with the visual scores (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.653, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CSKIN could serve as an alternative in the assessment and follow\u2010up of skin disease featuring with facial hyperpigmentation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/srt.13216","type":"journal-article","created":{"date-parts":[[2022,10,29]],"date-time":"2022-10-29T14:48:21Z","timestamp":1667054901000},"page":"846-850","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Assessment of features in facial hyperpigmentation: Comparison study between VISIA and CSKIN"],"prefix":"10.1111","volume":"28","author":[{"given":"Ying","family":"Zuo","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anqi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailun","family":"He","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoyu","family":"Wan","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology West China Hospital Sichuan University  Chengdu China"},{"name":"Cosmetic Safety and Efficacy Evaluation Center of West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.14747"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14824"},{"issue":"7","key":"e_1_2_9_4_1","first-page":"20","article-title":"Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color","volume":"3","author":"Davis EC","year":"2010","journal-title":"J Clin Aesthet 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practice","volume":"13","author":"Goldsberry A","year":"2014","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2014.3513"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000520753"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-016-0239-8"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.9b01413"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12616156"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470175637"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2020.102127"}],"container-title":["Skin Research and 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