{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T02:57:50Z","timestamp":1783306670866,"version":"3.54.6"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T00:00:00Z","timestamp":1718841600000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Acne vulgaris often results in permanent scars, with atrophic scars being the most common type and posing a significant therapeutic challenge due to their prevalence and impact on patients' quality of life. Various treatment options exist, including the use of poly\u2010\n                      <jats:sc>d,l<\/jats:sc>\n                      \u2010lactic acid delivered via different methods.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      This study aimed to assess the efficacy and safety of poly\u2010\n                      <jats:sc>d,l<\/jats:sc>\n                      \u2010lactic acid delivered via laser\u2010assisted needle\u2010free microjet injection for treating atrophic scars.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Five Korean participants with atrophic facial scars were recruited. Poly\u2010\n                      <jats:sc>d,l<\/jats:sc>\n                      \u2010lactic acid solution was administered via the Mirajet system in five sessions, with clinical assessments conducted at baseline, before each session, and at 12\u2010week and 22\u2010week follow\u2010ups. Outcome measures included the Global Aesthetic Improvement Scale and patient satisfaction scores.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Positive results were observed at the 12\u2010week and 22\u2010week follow\u2010ups, with high patient satisfaction and improvements in atrophic scars and skin texture. Mild discomfort and transient side effects were reported, with no adverse events observed during the follow\u2010up period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Poly\u2010\n                      <jats:sc>d,l<\/jats:sc>\n                      \u2010lactic acid delivered by a laser\u2010assisted needle\u2010free microjet injector was judged to be effective for improving atrophic the facial area. Further research, particularly through randomized controlled trials, is needed to validate these findings and assess the longer\u2010term safety and sustainability of outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/srt.13762","type":"journal-article","created":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T08:19:38Z","timestamp":1718871578000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Poly\u2010\n                    <scp>d,l\u2010<\/scp>\n                    lactic acid\u2010enhanced atrophic scar treatment via transdermal microjet drug delivery in Asians"],"prefix":"10.1111","volume":"30","author":[{"given":"Suk Bae","family":"Seo","sequence":"first","affiliation":[{"name":"SeoAhSong Dermatologic Clinic  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jovian","family":"Wan","sequence":"additional","affiliation":[{"name":"Asia\u2010Pacific Aesthetic Academy  Hong Kong Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa Kwin Wah","family":"Chan","sequence":"additional","affiliation":[{"name":"EverKeen Medical Centre  Hong Kong Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kar Wai Alvin","family":"Lee","sequence":"additional","affiliation":[{"name":"EverKeen Medical Centre  Hong Kong Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo\u2010Bin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Oral Biology Human Identification Research Institute Division in Anatomy and Developmental Biology BK21 FOUR Project Yonsei University College of Dentistry  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu\u2010Ho","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Oral Biology Human Identification Research Institute Division in Anatomy and Developmental Biology BK21 FOUR Project Yonsei University College of Dentistry  Seoul South Korea"},{"name":"Maylin Clinic (Apgujeong)  Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,20]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/893080"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-023-02737-9"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.13573"},{"key":"e_1_2_9_5_1","first-page":"12","article-title":"Acne scarring\u2010pathogenesis, evaluation, and treatment options","volume":"10","author":"Connolly D","year":"2017","journal-title":"J Clin Aesthet 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