{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:10Z","timestamp":1775606410729,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although observational studies have suggested a correlation between vitiligo and rheumatic diseases, conclusive evidence supporting a causal relationship is still lacking. Therefore, this study aims to explore the potential causal relationship between vitiligo and rheumatic diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using genome\u2010wide association studies, we performed a two\u2010sample Mendelian randomization (MR) analysis. In our analysis, the random\u2010effects inverse variance weighted (IVW) method was predominantly employed, followed by several sensitivity analyses, which include heterogeneity, horizontal pleiotropy, outliers, and \u201cleave\u2010one\u2010out\u201d analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The genetically predicted vitiligo was associated with an increased risk of rheumatoid arthritis (RA) (OR, 1.47; 95% confidence interval [CI], 1.29\u20131.68;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001), and systemic lupus erythematosus (SLE) (OR, 1.22; 95% CI, 1.06\u20131.39;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.005). The causal associations were supported by sensitivity analyses. In Sj\u00f6gren's syndrome and ankylosing spondylitis, no causal relationship with vitiligo was found in the study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our MR results support the causal effect that vitiligo leads to a higher risk of RA and SLE. Individuals with vitiligo should be vigilant for the potential development of RA and SLE. Managing and addressing this potential requires regular monitoring.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/srt.13846","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T06:54:15Z","timestamp":1720162455000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["RETRACTED: Identifying the genetic association between common rheumatic diseases and vitiligo"],"prefix":"10.1111","volume":"30","author":[{"given":"Mingming","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Hematology and Rheumatology The Fourth Affiliated Hospital Harbin Medical University  Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanyuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Hematology and Rheumatology The Fourth Affiliated Hospital Harbin Medical University  Harbin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guoxun","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Hematology and Rheumatology The Fourth Affiliated Hospital Harbin Medical University  Harbin 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