{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T01:31:36Z","timestamp":1771032696138,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T00:00:00Z","timestamp":1723507200000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Increasing studies have reported a causal relationship between androgenetic alopecia (AGA) and lipid\u2010related metabolites. However, the relationships between HDL\u2010C, LDL\u2010C, Omega\u20106, and Omega\u20103 with AGA remain unclear. Some research findings are even contradictory. Therefore, we designed this study to explore this issue.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this study, we selected seven exposure factors, screened SNPs with significant associations, removed linkage disequilibrium and weak instrumental variables, and conducted bidirectional MR analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study found that omega\u20106 and LDL\u2010C, especially total cholesterol in medium LDL and total cholesterol in small LDL, are risk factors for the occurrence of androgenetic alopecia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In summary, we found that various lipid\u2010related metabolites have a causal relationship with the occurrence of androgenetic alopecia, providing new insights into the pathogenesis of androgenetic alopecia and offering references for clinical treatment of androgenetic alopecia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/srt.70000","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T01:01:18Z","timestamp":1723597278000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["RETRACTED: Causal effects of omega\u20106 and LDL\u2010C on androgenetic alopecia: A Mendelian randomization study"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4716-2280","authenticated-orcid":false,"given":"Liu","family":"Peilong","sequence":"first","affiliation":[{"name":"The First Clinical Medical College Shandong University of Traditional Chinese Medicine Jinan Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5798-9428","authenticated-orcid":false,"given":"Zhao","family":"Quanlin","sequence":"additional","affiliation":[{"name":"General Internal Medicine Affiliated Hospital of Shandong University of Traditional Chinese Medicine Jinan Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gu","family":"Shuqing","sequence":"additional","affiliation":[{"name":"Internal Medicine People's Hospital of Xiajin County Xiajin China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,13]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Androgenetic Alopecia","author":"Ho CH","year":"2023"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S10182"},{"issue":"6","key":"e_1_2_9_4_1","first-page":"371","article-title":"Hair loss: common causes and treatment","volume":"96","author":"Phillips 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