{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T01:16:23Z","timestamp":1771377383644,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,8,21]],"date-time":"2024-08-21T00:00:00Z","timestamp":1724198400000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>As a common chronic recurrent inflammatory skin disease, psoriasis is characterized by erythema and scaly skin lesions, with infection as an integral part of the pathogenesis of many diseases. Many previous cases reported the impact of psoriasis on infection. However, the existing research fails to completely clarify the infection factors associated with the potential of these diseases and causality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>Thirteen kinds of pathogens and their immune responses and psoriasis in the phenotype of 46 species of SNPs data were respectively obtained from the GWAS catalog database and the UK biobank database. With the help of R software, three methods of inverse variance weighted (IVW), weighted median (WME), and MR\u2010Egger regression were used to analyze the causality of the dataset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      According to the results of IVW analysis, there is a causal relationship between anti\u2010Epstein Barr virus antibody and psoriasis (OR: 1.003, 95% CI: 1.001\u223c1.006,\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.046) with a positive correlation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Based on the results of MR analysis, there is a causal relationship between psoriasis and EBV infection, which indicates that EBV infection can increase the risk or severity of psoriasis. Therefore, in clinical scenarios, patients afflicted with psoriasis should be prevented from contracting the infection and recurrence of EBV as well as symptoms of psoriasis. The underlying immunological mechanism also provides a new perspective for experimental research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/srt.70002","type":"journal-article","created":{"date-parts":[[2024,8,21]],"date-time":"2024-08-21T22:58:44Z","timestamp":1724281124000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["RETRACTED: Association of partial infections with the risk of psoriasis: A two\u2010sample Mendelian randomization study"],"prefix":"10.1111","volume":"30","author":[{"given":"Minghui","family":"Lu","sequence":"first","affiliation":[{"name":"Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8110-3476","authenticated-orcid":false,"given":"Changyong","family":"Gao","sequence":"additional","affiliation":[{"name":"Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Runtian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingling","family":"Yuan","sequence":"additional","affiliation":[{"name":"Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi","family":"Chen","sequence":"additional","affiliation":[{"name":"Tongzhou Branch Dongzhimen Hospital, Beijing University of Chinese Medicine  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boping","family":"Zhang","sequence":"additional","affiliation":[{"name":"Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,8,21]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"1008","volume-title":"Chinese Clinical Dermatology","author":"Bian Z","year":"2017"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.26444\/aaem\/112107"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61909-7"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaa450"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.12895"},{"issue":"12","key":"e_1_2_10_7_1","first-page":"1352","article-title":"Atopic dermatitis and rheumatoid arthritis: a two\u2010sample bidirectional Mendelian randomization study","volume":"37","author":"Mingjing 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treatment of psoriasis and its local delivery systems","volume":"43","author":"Yiran C","year":"2022","journal-title":"World Clinical Drugs"},{"issue":"04","key":"e_1_2_10_23_1","first-page":"887","article-title":"Biological characteristics and pathogenic mechanisms of Epstein\u2010Barr virus","volume":"40","author":"Jun L","year":"2024","journal-title":"Virologica Sinica"},{"issue":"3","key":"e_1_2_10_24_1","first-page":"194","article-title":"Advances in research on STING\u2010represented innate immune signaling pathways in psoriasis","volume":"42","author":"Xiangzheng Li","year":"2023","journal-title":"Pharm 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