{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T19:38:19Z","timestamp":1790105899326,"version":"4.0.1"},"reference-count":43,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,8,21]],"date-time":"2024-08-21T00:00:00Z","timestamp":1724198400000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Skin Research and Technology"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Psoriasis is a prevalent inflammatory skin condition that can be recognized by silvery\u2010white scales on plaques and erythematous papules, despite the fact that psoriasis appears to have multiple causes.\n                      <jats:italic>Helicobacter pylori<\/jats:italic>\n                      (\n                      <jats:italic>H. pylori<\/jats:italic>\n                      ) has been investigated recently as a potential infectious etiological component.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>\n                      The objective of the study was to evaluate the prevalence of\n                      <jats:italic>H. pylori<\/jats:italic>\n                      infection in psoriatic patients compared to that of healthy controls and determine whether the degree of psoriasis and\n                      <jats:italic>H. pylori<\/jats:italic>\n                      infection were related.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>\n                      The dermatology, venerology, and andrology department at South Valley University Outpatient Clinic carried out this cross\u2010sectional study. Psoriatic patients of both sexes and ages were included. In addition to the control group,\n                      <jats:italic>H. Pylori<\/jats:italic>\n                      antigen was measured from psoriatic and control groups by using\n                      <jats:italic>H. pylori<\/jats:italic>\n                      stool antigen\u2010enzyme linked immunosorbent assay (HpSA\u2010ELISA), a test for\n                      <jats:italic>H. pylori<\/jats:italic>\n                      stool antigen. More than 20\u00a0ng\/mL of antigen proved positive, or less than 15\u00a0ng\/mL proved negative.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was a significant difference between psoriatic patients and control regarding\n                      <jats:italic>H. pylori<\/jats:italic>\n                      infection (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.046): (30.66%) positive in controls, (45.33%) positive in psoriatic patients. Both groups were matched for age (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.908), that is, the mean age of psoriatic patients was 37.44\u00a0\u00b1\u00a015.79 years, and the control group was 37.15\u00a0\u00b1\u00a015.15 years. Twenty\u2010five psoriatic patients in each group: mild, moderate, and severe psoriasis according to the Psoriasis Area Severity Index (PASI) score. No significant correlation between\n                      <jats:italic>H. pylori<\/jats:italic>\n                      infection and PASI, age, or duration of illness in psoriatic patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Patients with psoriasis had greater rates of\n                      <jats:italic>H. pylori<\/jats:italic>\n                      infection but didn't affect the severity of psoriasis.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/srt.70005","type":"journal-article","created":{"date-parts":[[2024,8,21]],"date-time":"2024-08-21T22:58:56Z","timestamp":1724281136000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<i>Helicobacter pylori<\/i>\n                    infection in psoriatic patients and its relation to psoriasis severity: Cross Sectional Study"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5394-6033","authenticated-orcid":false,"given":"Soheir","family":"Abdel\u2010Hamid","sequence":"first","affiliation":[{"name":"Dermatology, Venereology and Andrology Faculty of Medicine, South Valley University  Qena Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shimaa Arafat","family":"Abdel\u2010Monem","sequence":"additional","affiliation":[{"name":"Tropical medicine and gastroenterology Department Faculty of Medicine South Valley University  Qena Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,21]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1087-0024.2003.09102.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1590\/abd1806-4841.20174880"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.IJD_531_17"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina55100645"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqaa161.284"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(99)70112-X"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0804595"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18122526"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2001.00832.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2011.1579"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0b013e32834dda51"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2009.0739"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp038200"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i45.8188"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3758\/BF03193146"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000250839"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2003.09.014"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.28.706.49"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1534\/genetics.106.057042"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-11-32"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.08.015"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2007.08.015"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/hel.12411"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05562"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.2741\/3320"},{"issue":"1","key":"e_1_2_9_27_1","first-page":"13","article-title":"Prevalence 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