{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T16:04:14Z","timestamp":1759939454680},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T00:00:00Z","timestamp":1367798400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tissue Antigens"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Trichloroethylene (<jats:styled-content style=\"fixed-case\">TCE<\/jats:styled-content>)\u2010induced hypersensitivity dermatitis is one of the critical occupational diseases among workers in China. Our previous studies have identified a strong linkage between the disease and the <jats:italic><jats:styled-content style=\"fixed-case\">HLA\u2010B*13:01<\/jats:styled-content><\/jats:italic> allele. In this study, we searched for peptides bound to the <jats:italic><jats:styled-content style=\"fixed-case\">HLA\u2010B*13:01<\/jats:styled-content><\/jats:italic> molecule; 57 <jats:italic><jats:styled-content style=\"fixed-case\">HLA\u2010B*13:01<\/jats:styled-content><\/jats:italic>\u2010bound peptides in total were identified and 54 peptides were used to calculate frequency of amino acid residues to obtain binding motifs of <jats:italic><jats:styled-content style=\"fixed-case\">HLA\u2010B*13:01<\/jats:styled-content><\/jats:italic> molecule. The results showed <jats:styled-content style=\"fixed-case\">P2<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">P3<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">P9<\/jats:styled-content> were the primary binding anchor positions with the dominant anchor motifs of L, Q at <jats:styled-content style=\"fixed-case\">P2<\/jats:styled-content>, L at <jats:styled-content style=\"fixed-case\">P9<\/jats:styled-content>, D at <jats:styled-content style=\"fixed-case\">P3<\/jats:styled-content>. <jats:italic><jats:styled-content style=\"fixed-case\">HLA\u2010B*13:01<\/jats:styled-content><\/jats:italic>\u2010bound peptides were identified for the first time in our research, the results of which could contribute to the human leukocyte antigen (<jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>)\u2010binding peptides database.<\/jats:p>","DOI":"10.1111\/tan.12114","type":"journal-article","created":{"date-parts":[[2013,5,6]],"date-time":"2013-05-06T04:40:16Z","timestamp":1367815216000},"page":"442-448","source":"Crossref","is-referenced-by-count":9,"title":["Peptide\u2010binding motifs and characteristics for <i> HLA \u2010B*13:01<\/i> molecule"],"prefix":"10.1111","volume":"81","author":[{"given":"J.","family":"Zhang","sequence":"first","affiliation":[{"name":"Key laboratory of Chemical Safety and Health, Chinese Centre for Disease Control and Prevention, National Institute for Occupational Health and Poison Control Chinese Centre for Disease Control and Prevention  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, College of Basic Medical Sciences Hubei University of Chinese Medicine  Wuhan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Chemicals Safety Chinese Academy of Inspection and Quarantine  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Liu","sequence":"additional","affiliation":[{"name":"National Center of Biomedical Analysis  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Q.","family":"Jia","sequence":"additional","affiliation":[{"name":"Key laboratory of Chemical Safety and Health, Chinese Centre for Disease Control and Prevention, National Institute for Occupational Health and Poison Control Chinese Centre for Disease Control and Prevention  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Duan","sequence":"additional","affiliation":[{"name":"Key laboratory of Chemical Safety and Health, Chinese Centre for Disease Control and Prevention, 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