{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T04:25:44Z","timestamp":1758860744590},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,10,4]],"date-time":"2013-10-04T00:00:00Z","timestamp":1380844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Tissue Antigens"],"published-print":{"date-parts":[[2013,11]]},"abstract":"Abstract<\/jats:title>Studies of the effect of minor H antigen mismatching on the outcome of renal transplantation are scarce and concern mainly single center studies. The International Histocompatibility and Immunogenetics Workshops (IHIW<\/jats:styled-content>) provide a collaborative platform to execute crucial large studies. In collaboration with 16 laboratories of the IHIW<\/jats:styled-content>, the role of 15 autosomal, 10 Y\u2010chromosome encoded minor H antigens and 3 CD31<\/jats:styled-content> polymorphisms, was investigated in relation to the incidence of renal graft rejection and graft loss in 444 human leukocyte antigens (HLA<\/jats:styled-content>)\u2010identical sibling renal transplantations. Recipient and donor DNA<\/jats:styled-content> samples were genotyped for the minor H antigens HA<\/jats:styled-content>\u20101, HA<\/jats:styled-content>\u20102, HA<\/jats:styled-content>\u20103, HA<\/jats:styled-content>\u20108, HB<\/jats:styled-content>\u20101, ACC<\/jats:styled-content>\u20101, ACC<\/jats:styled-content>\u20102, SP110<\/jats:styled-content>, PANE1<\/jats:styled-content>, UGT2B17<\/jats:styled-content>, C19Orf48<\/jats:styled-content>, LB\u2010ECGF<\/jats:styled-content>\u20101, CTSH<\/jats:styled-content>, LRH<\/jats:styled-content>\u20101, LB\u2010ADIR<\/jats:styled-content> and HY<\/jats:styled-content>. The correlation between minor H antigen mismatch and the primary outcome graft rejection or graft loss was statistically analyzed. The incidence of rejection was very low and no correlation was observed between one or more minor H antigen mismatch(es) and a rejection episode (n<\/jats:italic>\u2009=\u200936), of which only eight resulted in graft loss. In summary, in our study cohort of 444 renal transplants, mismatching for neither autosomal nor HY<\/jats:styled-content> minor H antigens correlate with rejection episodes or with graft loss.<\/jats:p>","DOI":"10.1111\/tan.12209","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T02:02:07Z","timestamp":1381543327000},"page":"312-316","source":"Crossref","is-referenced-by-count":9,"title":["Minor H antigen matches and mismatches are equally distributed among recipients with or without complications after HLA<\/scp> identical sibling renal transplantation"],"prefix":"10.1111","volume":"82","author":[{"given":"M. P.","family":"Dierselhuis","sequence":"first","affiliation":[{"name":"Department of Immunohematology and Blood Transfusion Leiden University Medical Center Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Spierings","sequence":"additional","affiliation":[{"name":"Department of Immunology University Medical Center Utrecht Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Drabbels","sequence":"additional","affiliation":[{"name":"Department of Immunohematology and Blood Transfusion Leiden University Medical Center Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hendriks","sequence":"additional","affiliation":[{"name":"Department of Immunohematology and Blood Transfusion Leiden University Medical Center Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Alaez","sequence":"additional","affiliation":[{"name":"Department of Immunology & Immunogenetics Instituto de Diagnostico y Referencia Epidemiologicos Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Alber\u00fa","sequence":"additional","affiliation":[{"name":"Department of Transplantation Instituto Nacional de Ciencias, M\u00e9dicas y de la Nutrici\u00f3n Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. B.","family":"Alvarez","sequence":"additional","affiliation":[{"name":"Centro de Inmunolog\u00eda y Gen\u00e9tica molecular Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Burlingham","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Wisconsin Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Campos","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo and Associa\u00e7\u00e3o Fundo de Incentivo \u00e0 Pesquisa S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Christiaans","sequence":"additional","affiliation":[{"name":"Department of Nephrology Maastricht University Medical Center Maastricht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Claas","sequence":"additional","affiliation":[{"name":"Department of Immunohematology and Blood Transfusion Leiden University Medical Center Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. E.","family":"Fasano","sequence":"additional","affiliation":[{"name":"Immunologia Trapianti c\/o Genetica Turin Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Gerbase\u2010DeLima","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo and Associa\u00e7\u00e3o Fundo de Incentivo \u00e0 Pesquisa S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Gervais","sequence":"additional","affiliation":[{"name":"Immunohaematology, Cliniques St. Luc Universit\u00e9 Catholique de Louvain Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Gorodezky","sequence":"additional","affiliation":[{"name":"Department of Immunology & Immunogenetics Instituto de Diagnostico y Referencia Epidemiologicos Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Larriba","sequence":"additional","affiliation":[{"name":"Histocompatibility and Immunogenetics\u2014ICBME Hospital Italiano de Buenos Aires Buenos Aires Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. 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