{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T22:25:34Z","timestamp":1740176734383,"version":"3.37.3"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,4,17]],"date-time":"2017-04-17T00:00:00Z","timestamp":1492387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["HLA"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:p>Antibody identification by a bead array assay in a kidney patient revealed several <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010specific antibodies including one directed against the <jats:styled-content style=\"fixed-case\">HLA\u2010B7<\/jats:styled-content> antigen. Low\u2010resolution typing of the patient indicated the presence of an <jats:italic>\n<jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010B*07<\/jats:italic> allele. To rule out an <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010specific autoantibody the <jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010typing of the patient was further refined by nucleotide sequencing on a next\u2010generation sequencing platform and eventually showed an <jats:italic>\n<jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010B*39:01:01:03<\/jats:italic> and <jats:italic>\n<jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010B*07:<jats:styled-content style=\"fixed-case\">181N<\/jats:styled-content>\n<\/jats:italic> genotype. Thereby the allospecific nature of the antibody was proven. The <jats:styled-content style=\"fixed-case\">HLA\u2010B7<\/jats:styled-content>\u2010specific antibody could be explained by an immunization during the first kidney\u2010transplantation in 1996 with an <jats:italic>\n<jats:styled-content style=\"fixed-case\">HLA<\/jats:styled-content>\u2010B*07<\/jats:italic> positive donor. When assessing the plausibility of antibodies, the presence of nonexpressed alleles should be taken into consideration.<\/jats:p>","DOI":"10.1111\/tan.13045","type":"journal-article","created":{"date-parts":[[2017,4,18]],"date-time":"2017-04-18T01:46:45Z","timestamp":1492480005000},"page":"32-35","source":"Crossref","is-referenced-by-count":2,"title":["An <scp>HLA\u2010B7<\/scp>\u2010specific antibody in an <i><scp>HLA<\/scp>\u2010B*07<\/i> positive patient explained by a nonexpressed allele (<i>HLA\u2010B*07:181N<\/i>)"],"prefix":"10.1111","volume":"90","author":[{"given":"S.","family":"Wenda","sequence":"first","affiliation":[{"name":"Department for Blood Group Serology and Transfusion Medicine Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Fa\u00e9","sequence":"additional","affiliation":[{"name":"Department for Blood Group Serology and Transfusion Medicine Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3442-3680","authenticated-orcid":false,"given":"G. 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