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In total, we identified 8 HLA\u2010E, 5 HLA\u2010F, 8 HLA\u2010G, 15 HLA\u2010H, 39 MICA and 27 MICB alleles. Alleles with frequencies greater than 10% included\n                    <jats:italic>E*01:03, E*01:01, F*01:01, G*01:01, G*01:04, H*01:01, H*02:07, MICA*010:01, MICA*002:01, MICA*008:04, MICA*008:01, MICB*005:02<\/jats:italic>\n                    and\n                    <jats:italic>MICB*002:01<\/jats:italic>\n                    . Among the globally common alleles\n                    <jats:italic>E*01:03<\/jats:italic>\n                    and\n                    <jats:italic>E*01:01<\/jats:italic>\n                    ,\n                    <jats:italic>E*01:03<\/jats:italic>\n                    was more prevalent than\n                    <jats:italic>E*01:01<\/jats:italic>\n                    in Chinese and East Asian populations, whereas the opposite pattern was observed in African, European, Admixed American and South Asian populations. Subsequently, we identified 24 types of 17\u2010locus homozygous haplotypes. Although these homozygotes were present in only 0.53% of individuals, their cumulative haplotype frequency reached 12.57%. As the number of loci increased from 3 to 17, the homozygosity carrier rate declined from 1.46% to 0.53%, with a pronounced decrease observed after inclusion of the DPB1 locus. Notably, most of the homozygotes identified in this study had not been reported in the 18th International HLA &amp; Immunogenetics Workshop. For example, 26 of 27 types of 11\u2010locus homozygotes were previously unrecorded. The establishment of a database for HLA\u2010E, \u2010F, \u2010G, \u2010H, MICA and MICB alleles, as well as the distribution of homozygotes in the Chinese population, will provide valuable resources for genetic research, disease susceptibility, transplantation and cell therapy.\n                  <\/jats:p>","DOI":"10.1111\/tan.70620","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T08:43:21Z","timestamp":1773045801000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Distribution and\n                    <scp>CWD<\/scp>\n                    Categories of\n                    <scp>HLA<\/scp>\n                    \u2010E, \u2010F, \u2010G, \u2010H,\n                    <scp>MICA<\/scp>\n                    and\n                    <scp>MICB<\/scp>\n                    Alleles, as Well as Homozygotes Across 17 Loci in the Chinese Population"],"prefix":"10.1111","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3657-1035","authenticated-orcid":false,"given":"Yang","family":"Li","sequence":"first","affiliation":[{"name":"Department of HLA Laboratory, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianjie","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of HLA Laboratory, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoni","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of HLA Laboratory, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7939-2902","authenticated-orcid":false,"given":"Tengteng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of HLA Laboratory, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of HLA Laboratory, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingjie","family":"Li","sequence":"additional","affiliation":[{"name":"Department of HLA Laboratory, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"He","sequence":"additional","affiliation":[{"name":"Department of HLA Laboratory, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University  Suzhou Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojing","family":"Bao","sequence":"additional","affiliation":[{"name":"Department of HLA Laboratory, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology The First Affiliated Hospital of Soochow University  Suzhou Jiangsu 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