{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T04:47:58Z","timestamp":1772772478902,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T00:00:00Z","timestamp":1623369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006393","name":"Universidad de Granada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006393","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transbounding Emerging Dis"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Anthroponotic cutaneous leishmaniasis (ACL) due to <jats:italic>Leishmania tropica<\/jats:italic> is spreading to new areas in Morocco. Exposure to the vector, <jats:italic>Phlebotomus sergenti<\/jats:italic>, is the only proven risk factor. Our objective was to compare the densities and genetic characteristics of <jats:italic>P. sergenti<\/jats:italic> populations in two nearby localities in Morocco, one in an ACL endemic area (El Borouj) and another in a nonendemic area (Sidi Hajjaj). <jats:italic>P. sergenti<\/jats:italic> density was significantly higher in the endemic area than in the nonendemic town (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.032). A different predominant <jats:italic>P. sergenti<\/jats:italic> mitochondrial lineage was evidenced in each one of the two localities, and for the first time, the <jats:italic>P. sergenti<\/jats:italic> lineage acting as a vector of <jats:italic>L. tropica<\/jats:italic> has been identified. Bioclimatic differences were detected between both localities. In conclusion we found differences in both the density and the mitochondrial lineage of <jats:italic>P. sergenti<\/jats:italic> populations that may explain the different epidemiological situation. Given that the density of <jats:italic>P. sergenti<\/jats:italic> in the locality without ACL cases seems sufficient to allow transmission, the main factor that would justify its nonendemic character could be the absence of <jats:italic>P. sergenti<\/jats:italic> Lineage IV, which seems to prefer warmer and drier climates.<\/jats:p>","DOI":"10.1111\/tbed.14179","type":"journal-article","created":{"date-parts":[[2021,6,5]],"date-time":"2021-06-05T08:20:40Z","timestamp":1622881240000},"page":"1912-1921","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Understanding the factors that determine the emergence of anthroponotic cutaneous leishmaniasis due to <i>Leishmania tropica<\/i> in Morocco: Density and mitochondrial lineage of <i>Phlebotomus sergenti<\/i> in endemic and free areas of leishmaniasis"],"prefix":"10.1155","volume":"69","author":[{"given":"Patricia","family":"Gij\u00f3n\u2010Robles","sequence":"first","affiliation":[{"name":"Department of Parasitology Faculty of Pharmacy University of Granada  Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naima","family":"Abattouy","sequence":"additional","affiliation":[{"name":"Higher Institute of Nursing and Health Techniques  La\u00e2youne Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gemma","family":"Merino\u2010Espinosa","sequence":"additional","affiliation":[{"name":"Department of Parasitology Faculty of Pharmacy University of Granada  Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nora","family":"El Khalfaoui","sequence":"additional","affiliation":[{"name":"Laboratory of Cellular and Molecular Pathology\/Research Team on Immunopathology of Infectious and Systemic Diseases Hassan II University of Casablanca  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