{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T19:09:13Z","timestamp":1768590553888,"version":"3.49.0"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,7,17]],"date-time":"2021-07-17T00:00:00Z","timestamp":1626480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transbounding Emerging Dis"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Taenia solium<\/jats:italic> cysticercosis is a potentially eradicable neglected zoonotic disease with public health importance. The genetic lineages of <jats:italic>T.\u00a0solium<\/jats:italic> in Asia and Africa\/America are distinct and the genetic composition of the parasite was found to influence the clinical symptoms in patients with cysticercosis. In the present study, the <jats:italic>Cysticerci<\/jats:italic> collected from pigs of two southern states of India (Karnataka and Andhra Pradesh) were genetically characterized based on mitochondrial (COX 1 and Cyt b) and ribosomal (ITS\u20101 and TBR) DNA markers. The study confirms the existence of two mitochondrial lineages of the parasite as Asian and African\/American. Cytochrome oxidase 1 (COX 1) based analysis revealed the existence of two sub\u2010lineages of the parasite within the Asian lineage based on the polymorphism at 994 position as 994A\/G. In India, both the sub\u2010lineages were identified and genetic divergence among different Indian isolates was evident. Further, the sequence analysis of Cytochrome B (Cyt b) revealed the existence of six sub\u2010lineages of <jats:italic>T.\u00a0solium<\/jats:italic> in India as 69T\/69G, 97A\/97G as well as 264T\/264C. The analysis of nucleotide sequence of large subunit ribosomal DNA (TBR) revealed the existence of two sub\u2010lineages in India based on the deletion of a nucleotide at 624<jats:sup>th<\/jats:sup> position. The cysts collected in the present study were more closely related to those of China and Indonesia than with other Indian isolates. Further, the sequence analysis did not indicate the presence of <jats:italic>Taenia asiatica<\/jats:italic> in the examined pigs and African\/American lineages of <jats:italic>T.\u00a0solium<\/jats:italic>. The results of the present study help to better understand the genetic diversity of <jats:italic>T.\u00a0solium<\/jats:italic> in India.<\/jats:p>","DOI":"10.1111\/tbed.14227","type":"journal-article","created":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T22:49:25Z","timestamp":1625698165000},"page":"2256-2265","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Existence of genetic lineages within Asian genotype of <i>Taenia solium<\/i>\u2014Genetic characterization based on mitochondrial and ribosomal DNA markers"],"prefix":"10.1155","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0254-0102","authenticated-orcid":false,"given":"Siju Susan","family":"Jacob","sequence":"first","affiliation":[{"name":"Department of Parasitology ICAR\u2010National Institute of Veterinary Epidemiology and Disease Informatics, Yelahanka  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pinaki Prasad","family":"Sengupta","sequence":"additional","affiliation":[{"name":"Department of Parasitology ICAR\u2010National Institute of Veterinary Epidemiology and Disease Informatics, Yelahanka  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atru Gnana Surya","family":"Chandu","sequence":"additional","affiliation":[{"name":"Department of Parasitology ICAR\u2010National Institute of Veterinary Epidemiology and Disease Informatics, Yelahanka  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samer","family":"Shamshad","sequence":"additional","affiliation":[{"name":"Department of Parasitology ICAR\u2010National Institute of Veterinary Epidemiology and Disease Informatics, Yelahanka  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Revanaiah","family":"Yogisharadhya","sequence":"additional","affiliation":[{"name":"Department of Parasitology ICAR\u2010National Institute of Veterinary Epidemiology and Disease Informatics, Yelahanka  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subramanium","family":"Sudhagar","sequence":"additional","affiliation":[{"name":"Department of Parasitology ICAR\u2010National Institute of Veterinary Epidemiology and Disease Informatics, Yelahanka  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Palakurthi","family":"Ramesh","sequence":"additional","affiliation":[{"name":"Department of Parasitology ICAR\u2010National Institute of Veterinary Epidemiology and Disease Informatics, Yelahanka  Bengaluru India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,17]]},"reference":[{"issue":"10","key":"e_1_2_10_2_1","first-page":"1669","article-title":"Soft tissue cysticercosis: study of 21 cases","volume":"6","author":"Agrawal R.","year":"2012","journal-title":"Journal of clinical and diagnostic research"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1994.50.33"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2005.11.019"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.2307\/3284501"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.286.5437.128"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2015.08.006"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01734359"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-016-5211-2"},{"key":"e_1_2_10_10_1","unstructured":"Gemmell M. 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