{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T04:08:36Z","timestamp":1747714116074,"version":"3.40.5"},"reference-count":81,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,11,8]],"date-time":"2021-11-08T00:00:00Z","timestamp":1636329600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transbounding Emerging Dis"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Bovine leptospirosis is a bacterial disease that affects cattle herds, causing economic losses due to reproductive problems which require expensive treatments. The main source of transmission for cattle is still uncertain, but rodents and bats can play an important role in the transmission cycle by being maintenance hosts for the pathogenic species of the bacterium and spreading it through urine. In this study, we characterize possible risk areas for bovine leptospirosis exposure in the state of Veracruz, Mexico, based on the geographical distribution of flying (bats) and terrestrial (rodents and opossums) wild hosts of <jats:italic>Leptospira<\/jats:italic> sp. reported in Mexico, in addition to climate, geography, soil characteristics, land use and human activities (environmental variables). We used a generalized linear regression model to understand the association between the frequency of anti\u2010<jats:italic>Leptospira<\/jats:italic> sp. antibodies (a proxy of exposure) in cattle herds exposed to <jats:italic>Leptospira<\/jats:italic>, the favourability of wild hosts of <jats:italic>Leptospira<\/jats:italic> as well as the environmental variables. The parameterized model explained 12.3% of the variance. The frequency of anti\u2010<jats:italic>Leptospira<\/jats:italic> sp. antibodies exposure in cattle herds was associated with elevation, geographic longitude, pH of the soil surface and environmental favourability for the presence of rodents, opossums and bats. The variation in exposure was mainly explained by a longitudinal gradient (6.4% of the variance) and the favourability\u2010based indices for wild hosts (9.6% of the variance). Describing the possible risks for exposure to <jats:italic>Leptospira<\/jats:italic> in an important and neglected livestock geographical region, we provide valuable information for the selection of areas for diagnosis and prevention of this relevant disease.<\/jats:p>","DOI":"10.1111\/tbed.14346","type":"journal-article","created":{"date-parts":[[2021,10,17]],"date-time":"2021-10-17T23:41:48Z","timestamp":1634514108000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Spatial epidemiology of <i>Leptospira<\/i> sp. exposure in bovines from Veracruz, M\u00e9xico"],"prefix":"10.1155","volume":"69","author":[{"given":"Rigoberto","family":"Guti\u00e9rrez\u2010Molina","sequence":"first","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia Universidad Veracruzana  Veracruz M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pelayo","family":"Acevedo","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n en Recursos Cineg\u00e9ticos, IREC (UCLM\u2010CSIC\u2010JCCM)  Ciudad Real Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6316-2187","authenticated-orcid":false,"given":"Sokani","family":"S\u00e1nchez\u2010Montes","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Biol\u00f3gicas y Agropecuarias regi\u00f3n Tuxpan Universidad Veracruzana  Tuxpan Veracruz M\u00e9xico"},{"name":"Centro de Medicina Tropical Unidad de Investigaci\u00f3n en Medicina Experimental Facultad de Medicina Universidad Nacional Aut\u00f3noma de M\u00e9xico  Mexico City M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dora","family":"Romero\u2010Salas","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia Universidad Veracruzana  Veracruz M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"L\u00f3pez\u2010Ortiz","sequence":"additional","affiliation":[{"name":"Colegio de Postgraduados Campus Veracruz  Veracruz M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Argel","family":"Flores\u2010Primo","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia Universidad Veracruzana  Veracruz M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4080-6722","authenticated-orcid":false,"given":"Anabel","family":"Cruz\u2010Romero","sequence":"additional","affiliation":[{"name":"Facultad de Medicina Veterinaria y Zootecnia Universidad Veracruzana  Veracruz M\u00e9xico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,8]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddi.12589"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102699.2012.02713.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00114\u2010012\u20100926\u20100"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4612-1694-0_16"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006444"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/tbed.12802"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecolmodel.2011.02.011"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoinf.2013.11.002"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0227055"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1612.100557"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0007499"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/aesa\/saz048"},{"issue":"4","key":"e_1_2_9_14_1","first-page":"277","article-title":"Detecci\u00f3n de Leptospira santarosai y L. kirschneri en bovinos: Nuevos aislados con potencial impacto en producci\u00f3n bovina y salud p\u00fablica","volume":"42","author":"Carmona\u2010Gasca C. A.","year":"2011","journal-title":"Veterinaria M\u00e9xico"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1353\/book.36904"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens9070573"},{"key":"e_1_2_9_17_1","unstructured":"Comisi\u00f3n Nacional para el Conocimiento y Uso de la Biodiversidad (CONABIO). (2020).Portal de Geoinformaci\u00f3n.http:\/\/www.conabio.gob.mx\/informacion\/gis\/"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201064172\u20104"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003898"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1556\/1886.2018.00009"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/tbed.12643"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/zph.12549"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.138251"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005176"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004097"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph110606000"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/01650521.2016.1273751"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.01174"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0036\u201046652015000200015"},{"volume-title":"Leptospira and leptospirosis","year":"2000","author":"Faine S.","key":"e_1_2_9_30_1"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2017.03.032"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/joc.5086"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0125801"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph111010366"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.12933\/therya\u201019\u2010723"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002270"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100587.2009.06428.x"},{"volume-title":"Applied logistic regression","year":"1989","author":"Hosmer D. W. J.","key":"e_1_2_9_38_1"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/0471722146"},{"key":"e_1_2_9_40_1","unstructured":"Instituto Nacional de Estad\u00edstica y Geograf\u00eda (INEGI). (2017).Encuesta Nacional Agropecuaria 2017.Instituto Nacional de Estad\u00edstica y Geograf\u00eda."},{"key":"e_1_2_9_41_1","unstructured":"Instituto Nacional de Estad\u00edstica y Geograf\u00eda (INEGI). (2020).Datos.https:\/\/www.inegi.org.mx\/datos\/"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/tbed.13306"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/geb.12007"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tree.2019.03.004"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2208"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/vms3.255"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16122113"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1466\u20108238.2007.00358.x"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph110707242"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/trstmh\/trz124"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/mam.12074"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304\u20103800(00)00322\u20107"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00114\u2010008\u20100352\u20105"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro.2017.5"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11250\u2010018\u20101512\u2010z"},{"key":"e_1_2_9_56_1","unstructured":"QGIS Development Team. (2020).QGIS Geographic Information System. Open Source Geospatial Foundation Project.http:\/\/qgis.org"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1186\/2046\u20100481\u201065\u20106"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10651\u2010005\u20100003\u20103"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071\u2010019\u20103691\u20105"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0036\u201046652002000400011"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0133720"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006415"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11250\u2010010\u20109607\u20101"},{"key":"e_1_2_9_64_1","unstructured":"Servicio de Informaci\u00f3n Agroalimentaria y Pesquera (SIAP). (2018).Anuario Estad\u00edstico de la Producci\u00f3n Ganadera.https:\/\/nube.siap.gob.mx\/cierre_pecuario\/"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bti623"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134\u2010019\u201005839\u2010z"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00816"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0004122"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.7705\/biomedica.v38i3.3938"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.21897\/rmvz.1815"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecolind.2020.106565"},{"issue":"3","key":"e_1_2_9_72_1","first-page":"193","article-title":"Determinaci\u00f3n de leptospirosis en roedores y marsupiales de la regi\u00f3n sur del lago de Maracaibo, estado M\u00e9rida, Venezuela","author":"Valbuena\u2010Torrealba C.","year":"2015","journal-title":"Revista Cientifica FCV\u2010LUZ"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11250\u2010017\u20101429\u2010y"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0007270"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.4322\/natcon.2012.035"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-98141-3"},{"key":"e_1_2_9_77_1","unstructured":"World Health Organization. (2010).Report of the first meeting of the Leptospirosis Burden Epidemiology Reference Group.Author."},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16061042"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.21640\/ns.v7i14.112"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010016\u20101653\u20105"},{"issue":"2","key":"e_1_2_9_81_1","first-page":"71","article-title":"Panorama epidemiol\u00f3gico de la leptospirosis, Estados Unidos Mexicanos 2000\u20132010","volume":"33","author":"Zu\u00f1iga\u2010Carrasco I. R.","year":"2013","journal-title":"Enfermedades Infecciosas y Microbiologia"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-87458-6"}],"container-title":["Transboundary and Emerging Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tbed.14346","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tbed.14346","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tbed.14346","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T17:25:12Z","timestamp":1747675512000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tbed.14346"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,8]]},"references-count":81,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1111\/tbed.14346"],"URL":"https:\/\/doi.org\/10.1111\/tbed.14346","archive":["Portico"],"relation":{},"ISSN":["1865-1674"],"issn-type":[{"type":"print","value":"1865-1674"}],"subject":[],"published":{"date-parts":[[2021,11,8]]},"assertion":[{"value":"2021-05-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}