{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T11:15:17Z","timestamp":1770290117181,"version":"3.49.0"},"reference-count":59,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,4,12]],"date-time":"2022-04-12T00:00:00Z","timestamp":1649721600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transbounding Emerging Dis"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Border disease (BD) was first reported in 1959 in lambs from the border region of England and Wales. The causative virus (BD virus; BDV) has since been identified in several other ruminant species and pigs. The virus is prevalent in sheep flocks of UK, Europe and USA and has potential to inflict substantial economic losses. Natural BDV infection of pigs was first reported in the UK in 1992 from pigs with haemorrhagic lesions and more recently from healthy pigs in Spain and Japan. Here, a persistent problem of poor growth and anaemia in a small proportion of growing pigs on a mixed pig and sheep holding was investigated and tissues were tested in a pan viral microarray. The microarray detected BDV RNA in several tissues which was further confirmed by sequencing, specific BDV PCR and immunohistochemistry. Phylogenetically, the virus clustered with other BDVs in the sub\u2010genotype 1b. This investigation highlights likely interspecies transmission of pestiviruses and their impact on pestivirus detection and eradication programs.<\/jats:p>","DOI":"10.1111\/tbed.14539","type":"journal-article","created":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T14:24:00Z","timestamp":1648650240000},"page":"1698-1706","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Investigation into an outbreak of Border disease virus in pigs in England"],"prefix":"10.1155","volume":"69","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6251-6588","authenticated-orcid":false,"given":"Akbar","family":"Dastjerdi","sequence":"first","affiliation":[{"name":"Virology Department Animal and Plant Health Agency (APHA)\u2010Weybridge  Addlestone Surrey UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"Strong","sequence":"additional","affiliation":[{"name":"Virology Department Animal and Plant Health Agency (APHA)\u2010Weybridge  Addlestone Surrey UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Anna","family":"La Rocca","sequence":"additional","affiliation":[{"name":"Virology Department Animal and Plant Health Agency (APHA)\u2010Weybridge  Addlestone Surrey UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Wessels","sequence":"additional","affiliation":[{"name":"APHA\u2010Preston Animal Health Centre  Barton Preston UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Wessels","sequence":"additional","affiliation":[{"name":"APHA\u2010Bury St. Edmunds  Suffolk UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Whitaker","sequence":"additional","affiliation":[{"name":"APHA\u2010Preston Animal Health Centre  Barton Preston UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben","family":"Strugnell","sequence":"additional","affiliation":[{"name":"APHA\u2010Thirsk West House  Thirsk UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanna","family":"Williamson","sequence":"additional","affiliation":[{"name":"APHA\u2010Preston Animal Health Centre  Barton Preston UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,4,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0042\u20106822(03)00192\u20102"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-78-6-1357"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1994.1065"},{"key":"e_1_2_9_5_1","first-page":"90","article-title":"Sporadic cases of multiple haemorrhages in pigs","volume":"68","author":"Bidewell C.","year":"2013","journal-title":"Pig Journal"},{"issue":"3","key":"e_1_2_9_6_1","first-page":"293","article-title":"Attempt to adapt the lapinized hog cholera virus strain \u201cSuvac\u201d to sheep","volume":"16","author":"Bir\u00f3 J.","year":"1966","journal-title":"Acta Veterinaria Academiae Scientiarum Hungaricae"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2018.00031"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705\u2010016\u20103112\u20104"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-6148-8-204"},{"key":"e_1_2_9_10_1","unstructured":"Centre for Food Security and Public Health (CFSPH). (2015).Classical Swine Fever.Factsheets. Available viawww.cfsph.iastate.edu"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.100497"},{"key":"e_1_2_9_12_1","volume-title":"Laboratory techniques in rabies diagnosis, research and prevention","author":"Dastjerdi A.","year":"2016"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0121718"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022\u20101317\u201069\u20101\u201077"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2008.01.002"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063870802000305"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166\u20100934(94)90189\u20109"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1558-5646.1985.tb00420.x"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098588902600105"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01933\u201014"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300985812447827"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1135(90)90150-T"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439\u20100450.1995.tb00748.x"},{"issue":"7","key":"e_1_2_9_24_1","first-page":"286","article-title":"New real\u2010time reverse transcriptase polymerase chain reactions facilitate detection and differentiation of novel A\/H1N1 influenza virus in porcine and human samples","volume":"123","author":"Hoffmann B.","year":"2010","journal-title":"Berliner Und Munchener Tierarztliche Wochenschrift"},{"key":"e_1_2_9_25_1","first-page":"313","article-title":"B\u201d or border disease. An undescribed disease of sheep","volume":"71","author":"Hughes L. E.","year":"1959","journal-title":"The Veterinary Record"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2014.03.032"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msy096"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063870501700211"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1863\u20102378.2007.01049.x"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2009.06.005"},{"key":"e_1_2_9_31_1","first-page":"807","article-title":"Propagation and transmission of hog cholera virus in non\u2010porcine hosts","volume":"29","author":"Loan R. W.","year":"1968","journal-title":"American Journal of Veterinary Research"},{"issue":"5","key":"e_1_2_9_32_1","first-page":"225","article-title":"Leukopenia and thrombocytopenia in pigs after infection with bovine viral diarrhoea virus\u20102 (BVDV\u20102)","volume":"109","author":"Makoschey B.","year":"2002","journal-title":"Deutsche Tierarztliche Wochenschrift"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0166\u20100934(99)00010\u20105"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.44-5-643"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2008.09.085"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.164.25.771"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/1297\u20109716\u201045\u201038"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2012.02.008"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9975(05)80047-7"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9975(05)80076-3"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/151.2.337"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvfa.2009.10.007"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378\u20101135(92)90051\u2010t"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.101920"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102672.2012.05384.x"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1135(89)90044-8"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.000873"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2005.01.020"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2009.09.010"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0168\u20101702(96)01402\u20105"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1029\/96PA03934"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.aivir.2015.03.002"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300985810371309"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2006.10.002"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.1998.36048"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022\u20101317\u201078\u20104\u2010725"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9975(05)80034-9"},{"key":"e_1_2_9_58_1","doi-asserted-by":"crossref","first-page":"269","DOI":"10.2460\/ajvr.1991.52.02.269","article-title":"Lesions and localization of viral antigen in tissues of cattle with experimentally induced or naturally acquired mucosal disease, or with naturally acquired chronic bovine viral diarrhea","volume":"52","author":"Wilhelmsen C. L.","year":"1991","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439\u20100450.1992.tb01211.x"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.02562"}],"container-title":["Transboundary and Emerging Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tbed.14539","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/tbed.14539","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/tbed.14539","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T17:08:52Z","timestamp":1747674532000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tbed.14539"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,12]]},"references-count":59,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1111\/tbed.14539"],"URL":"https:\/\/doi.org\/10.1111\/tbed.14539","archive":["Portico"],"relation":{},"ISSN":["1865-1674"],"issn-type":[{"value":"1865-1674","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4,12]]},"assertion":[{"value":"2021-11-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}