{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T12:21:56Z","timestamp":1761740516105},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,11,23]],"date-time":"2012-11-23T00:00:00Z","timestamp":1353628800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The prevalence of <jats:italic><jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ycobacterium tuberculosis<\/jats:italic> in transplant recipients is estimated to be 50 times higher than in the general population, with a mortality rate of around 40%. Diagnosis and treatment of latent tuberculosis (<jats:styled-content style=\"fixed-case\">TB<\/jats:styled-content>) infection (<jats:styled-content style=\"fixed-case\">LTBI<\/jats:styled-content>) is an essential strategy for <jats:styled-content style=\"fixed-case\">TB<\/jats:styled-content> control. In this study we compared the Quanti<jats:styled-content style=\"fixed-case\">FERON<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">TB<\/jats:styled-content> Gold In\u2010Tube test (<jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content>) with the tuberculin skin test (<jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content>) for detection of <jats:styled-content style=\"fixed-case\">LTBI<\/jats:styled-content> in solid organ transplant (<jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content>) candidates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>Between <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch 2008 and <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>eptember 2011, 187 transplant candidates, who were referred to the transplant clinic of <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>mam\u2010<jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>homeini <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ospital, were enrolled in the study. Patients were screened for <jats:styled-content style=\"fixed-case\">LTBI<\/jats:styled-content> with both <jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content>. Twenty\u2010three patients (12.3%) were excluded for failure to follow up. Concordance between the 2 tests, and variables associated with test discordance were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of patients was 40\u00a0years (range: 11\u201365) and male\u2010to\u2010female ratio was 1.2 (88\/76). <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content> were positive in 26 (15.9%) and 33 (20.1%) patients, respectively. Five cases (3.1%) had indeterminate <jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content>. Overall agreement between <jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content> was about 80% (<jats:italic>k<\/jats:italic>\u00a0=\u00a00.32, <jats:italic>P<\/jats:italic>\u2010value\u00a0=\u00a00.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Considering the fair overall agreement between the 2 tests, and greater ease of the <jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content> from the patient's point of view, <jats:styled-content style=\"fixed-case\">QFT<\/jats:styled-content> is recommended for detection of <jats:styled-content style=\"fixed-case\">LTBI<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">SOT<\/jats:styled-content> candidates.<\/jats:p><\/jats:sec>","DOI":"10.1111\/tid.12027","type":"journal-article","created":{"date-parts":[[2012,11,23]],"date-time":"2012-11-23T04:39:31Z","timestamp":1353645571000},"page":"90-95","source":"Crossref","is-referenced-by-count":19,"title":["Quanti<scp>FERON<\/scp>\u2010<scp>TB<\/scp> Gold In\u2010Tube test for diagnosis of latent tuberculosis (<scp>TB<\/scp>) infection in solid organ transplant candidates: a single\u2010center study in an area endemic for <scp>TB<\/scp>"],"prefix":"10.1111","volume":"15","author":[{"given":"Z.","family":"Ahmadinejad","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases Imam\u2010Khomeini Hospital Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Azmoudeh Ardalan","sequence":"additional","affiliation":[{"name":"Department of Pathology Imam\u2010Khomeini Complex Hospital Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Razzaqi","sequence":"additional","affiliation":[{"name":"Iranian Tissue Bank Research &amp; Preparation Center Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Davoudi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Imam\u2010Khomeini Hospital Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Jafarian","sequence":"additional","affiliation":[{"name":"Department of Surgery Imam\u2010Khomeini Hospital Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,11,23]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"World Health Organization.Global tuberculosis control: 2010 report. 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