{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T13:29:08Z","timestamp":1776691748997,"version":"3.51.2"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,12,26]],"date-time":"2012-12-26T00:00:00Z","timestamp":1356480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic><jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ycobacterium tuberculosis<\/jats:italic> infection is one of many opportunistic infections in renal transplant recipients, arising either from reactivation of latent infection or <jats:italic>de novo<\/jats:italic> infection, occasionally donor derived. <jats:italic><jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>.\u00a0tuberculosis<\/jats:italic> hepatitis has never been reported in patients who have received alemtuzumab as part of their renal transplant management. We describe 2 patients who underwent deceased\u2010donor renal transplantation following alemtuzumab induction therapy and presented with a febrile syndrome, subsequently diagnosed as tuberculous hepatitis, one with disseminated disease. Both responded well to treatment without significant side effects, resulting in excellent graft function. The importance of chemoprophylaxis should be emphasized to minimize the risk of developing active tuberculosis in patients with latent tuberculosis infection undergoing solid organ transplantation.<\/jats:p>","DOI":"10.1111\/tid.12048","type":"journal-article","created":{"date-parts":[[2012,12,27]],"date-time":"2012-12-27T02:56:10Z","timestamp":1356576970000},"source":"Crossref","is-referenced-by-count":13,"title":["Tuberculous hepatitis in renal transplant recipients following alemtuzumab induction therapy"],"prefix":"10.1111","volume":"15","author":[{"given":"W.","family":"Bosch","sequence":"first","affiliation":[{"name":"Division of Infectious Disease Mayo Clinic Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Poowanawittayakom","sequence":"additional","affiliation":[{"name":"Department of Medicine Siriraj Hospital Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Chaikriangkrai","sequence":"additional","affiliation":[{"name":"Department of Medicine Siriraj Hospital Mahidol University Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Mendez","sequence":"additional","affiliation":[{"name":"Division of Infectious Disease Mayo Clinic Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.C.","family":"Hellinger","sequence":"additional","affiliation":[{"name":"Division of Infectious Disease Mayo Clinic Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.A.","family":"Gonwa","sequence":"additional","affiliation":[{"name":"Department of Transplantation Mayo Clinic Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Krishna","sequence":"additional","affiliation":[{"name":"Department of Pathology Mayo Clinic Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Pungpapong","sequence":"additional","affiliation":[{"name":"Department of Transplantation Mayo Clinic Jacksonville Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,12,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181fecfcb"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2008.00346.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TP.0000109643.32659.C4"},{"issue":"11","key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1681\/ASN.V8111771","article-title":"Effect of anti\u2010lymphocyte induction therapy on renal allograft survival: a meta\u2010analysis","volume":"8","author":"Szczech LA","year":"1997","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-128-10-199805150-00004"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1009546"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2008.02273.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000189713.14993.db"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2004.06.015"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra064928"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2007.06.010"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1592\/phco.28.2.281"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1411.071321"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2007.00292.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2009.00475.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2004.00263.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199601270-00008"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2011.05.032"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02894.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2004.00545.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2012.00737.x"},{"key":"e_1_2_7_23_1","volume-title":"Global Tuberculosis Control: WHO Report 2011","author":"World Health Organization, Global Tuberculosis Programme","year":"2011"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0b013e3181ecea8d"},{"issue":"17","key":"e_1_2_7_25_1","first-page":"1791","article-title":"Trends in Tuberculosis\u2013United States, 2011 (Reprinted from MMWR, 2012; 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