{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T23:54:23Z","timestamp":1767830063301,"version":"3.49.0"},"reference-count":28,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,6,19]],"date-time":"2013-06-19T00:00:00Z","timestamp":1371600000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Necrotizing soft tissue infections (<jats:styled-content style=\"fixed-case\">NSTI<\/jats:styled-content>) are rare but carry high mortality rates. <jats:styled-content style=\"fixed-case\">NSTI<\/jats:styled-content> with <jats:italic><jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>lebsiella<\/jats:italic> species have been previously described as associated with <jats:italic><jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>lebsiella<\/jats:italic> liver abscesses and endophthalmitis. Here, we describe 6 cases of <jats:styled-content style=\"fixed-case\">NSTI<\/jats:styled-content> in liver transplant recipients associated with <jats:italic><jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>lebsiella pneumoniae<\/jats:italic>, 4 of which were <jats:italic><jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>.\u00a0pneumoniae<\/jats:italic> carbapenemase (<jats:styled-content style=\"fixed-case\">KPC<\/jats:styled-content>)\u2010producing <jats:italic><jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>.\u00a0pneumoniae<\/jats:italic> (<jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content>). Increased awareness of this emerging pathogen and its association with necrotizing skin and soft tissue infection is critical, as early recognition and debridement may improve survival. Antimicrobial treatment of <jats:styled-content style=\"fixed-case\">CRKP<\/jats:styled-content> infections remains an ongoing challenge and implementation of enhanced infection control measures is essential.<\/jats:p>","DOI":"10.1111\/tid.12103","type":"journal-article","created":{"date-parts":[[2013,6,19]],"date-time":"2013-06-19T11:58:09Z","timestamp":1371643089000},"source":"Crossref","is-referenced-by-count":18,"title":["<i>Klebsiella<\/i> necrotizing soft tissue infections in liver transplant recipients: a case series"],"prefix":"10.1111","volume":"15","author":[{"given":"M.M.","family":"Rana","sequence":"first","affiliation":[{"name":"Department of Medicine Mount Sinai School of Medicine New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sturdevant","sequence":"additional","affiliation":[{"name":"Department of Surgery University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Medicine Mount Sinai School of Medicine New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Huprikar","sequence":"additional","affiliation":[{"name":"Department of Medicine Mount Sinai School of Medicine New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,6,19]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1086\/511638"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2008.10.032"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0b013e32825a6a1b"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1086\/517760"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1086\/313471"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e3181a393a4"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2006.007"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1086\/313791"},{"issue":"10","key":"e_1_2_5_10_1","first-page":"256","article-title":"Guidance for control of infections with carbapenem\u2010resistant or carbapenemase\u2010producing Enterobacteriaceae in acute care facilities","volume":"58","author":"CDC","year":"2009","journal-title":"MMWR"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-004-1125-5"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/18.1.195"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(98)01056-2"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2008.07.028"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3046.2002.00210.x"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2012.00742.x"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2011.00697.x"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1201-9712(00)90072-9"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1086\/592412"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0b013e3283404373"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/lt.23374"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2010.02.001"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e3283558c17"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e32833b3571"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2011.08.004"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2011.00688.x"},{"key":"e_1_2_5_27_1","unstructured":"CDC.Guidance for control of carbapenem\u2010resistant Enterobacteriaceae (CRE). 2012 CRE toolkit. 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