{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T20:42:03Z","timestamp":1765485723059},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,6,23]],"date-time":"2013-06-23T00:00:00Z","timestamp":1371945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplant Infectious Dis"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cytomegalovirus (<jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>) can cause severe infections with serious consequences in renal transplant recipients. Disseminated <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infections can affect almost every organ, but obstructive cholestasis and cholangitis, as a consequence of a <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\u2010induced papillitis, is extremely rare. We are reporting a rare case of obstructive cholestasis and cholecystitis due to <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\u2010related inflammation of the major duodenal papilla in a 60\u2010year\u2010old woman 3\u00a0months after renal transplantation. In addition, the patient suffered from a disseminated <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection with ulcerative esophagitis and gastritis. Because of the severe <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content> infection, failure of the renal graft occurred. Obstructive cholestasis was resolved through internal stenting, and the progressive cholecystitis necessitated an emergency cholecystectomy. Following antiviral therapy with ganciclovir, the gastrointestinal ulcerations regressed and renal function was restored. Diagnosis of the <jats:styled-content style=\"fixed-case\">CMV<\/jats:styled-content>\u2010related disease was established only in tissue samples, whereas standard serologic tests had failed.<\/jats:p>","DOI":"10.1111\/tid.12105","type":"journal-article","created":{"date-parts":[[2013,6,24]],"date-time":"2013-06-24T02:25:25Z","timestamp":1372040725000},"source":"Crossref","is-referenced-by-count":12,"title":["Cytomegalovirus infection of the major duodenal papilla in a renal allograft recipient with severe biliary obstruction and acalculous cholecystitis"],"prefix":"10.1111","volume":"15","author":[{"given":"C.","family":"Riediger","sequence":"first","affiliation":[{"name":"Department of Hepatology, Gastroenterology, and Infectious Diseases University of Heidelberg Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Beimler","sequence":"additional","affiliation":[{"name":"Department of Nephrology University of Heidelberg Heidelberg 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